Zur Spaltbarkeit verschiedener Naphthol-Carbons�ureester durch Esterasen im Tanycytenependym des III. Ventrikels der Wistarratte

Goslar, H. G.; Böck, R.

doi:10.1007/bf00280904

Cited by 25 publications

(5 citation statements)

References 12 publications

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“…8). Tanycytes have been shown to contain GABA decarboxylase (Goslar & Bock, 1970) and these may function as glial cells and remove the GABA as a means of terminating its action.…”

Section: Discussionmentioning

confidence: 99%

Effect of Various Putative Neurotransmitters on the Secretion of Corticotrophin-Releasing Hormone From the Rat Hypothalamus in Vitro – A Model of the Neurotransmitters Involved

Jones¹,

Hillhouse²,

Burden³

1976

Journal of Endocrinology

275

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The effect of incubating the hypothalamus of adult male rats with various neurotransmitters upon the release of corticotrophin-releasing hormone (CRH) was studied. The CRH activity in the incubation medium was assayed in 48 h median eminence-lesioned rats and the corticosteroidogenesis of excised adrenals in vitro was used as the end-point. 5-Hydroxytryptamine (100 pg/ml-10ng/ml) caused a dose-dependent release of CRH which was antagonized by methysergide (30-100 ng/ml). The response to 5-hydroxytryptamine was also inhibited by hexamethonium and atropine which indicated that it was acting through a cholinergic interneurone. Melatonin (10 ng) did not alter the basal release of CRH but inhibited the action of both 5-hydroxytryptamine (10 ng) and acetylcholine (3 pg). Thus it appears that both 5-hydroxytryptamine and melatonin play a role in the control of CRH release. Noradrenaline blocked the release of CRH induced by both acetylcholine and 5-hydroxytryptamine and presumably this inhibition was caused by direct action on the CRH neurone. gamma-Aminobutyric acid (GABA) also inhibited the release of CRH and may also be involved in the regulation of CRH secretion. The inhibitory neurotransmitters, noradrenaline, GABA and melatonin, act via independent receptor mechanisms. A model based on the above data is presented.

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“…8). Tanycytes have been shown to contain GABA decarboxylase (Goslar & Bock, 1970) and these may function as glial cells and remove the GABA as a means of terminating its action.…”

Section: Discussionmentioning

confidence: 99%

Effect of Various Putative Neurotransmitters on the Secretion of Corticotrophin-Releasing Hormone From the Rat Hypothalamus in Vitro – A Model of the Neurotransmitters Involved

Jones¹,

Hillhouse²,

Burden³

1976

Journal of Endocrinology

275

View full text Add to dashboard Cite

show abstract

“…Early enzyme histochemical studies had shown that a tanycytes diVer from b tanycytes and react diVerently to adrenalectomy (Bock and Goslar, 1969;Goslar and Bock, 1970). A light and electron microscopic analysis of the distribution of adenosine triphosphatase has shown that this enzyme is abundant in the tanycytes facing the ventromedial nucleus (a 1 tanycytes) and is not detectable in the tanycytes facing the arcuate nucleus (a 2 tanycytes) or those of the median eminence (b 1,2 tanycytes) (Firth and Bock, 1976).…”

Section: B Morphology and Cytochemistrymentioning

confidence: 99%

Hypothalamic Tanycytes: A Key Component of Brain–Endocrine Interaction

Rodríguez

Blázquez

Pastor

et al. 2005

International Review of Cytology

424

484

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“…Only a few histochemical studies of the ependyma of the median eminence have been made (Bock & Goslar, 1969;Goslar & Bock, 1970). In some birds the basal processes of the median eminence ependyma are loaded with aldehyde fuchsin-positive material (Oksche, Laws, nence include Bern et al (1966), Matsui (1966a,¿>), Wittkowski (1967aWittkowski ( , 1969, Matsui & Kobayashi (1968), Rodriguez (1968Rodriguez ( , 1969ft, 1972, Calas & Assenmacher (1970), , Kobayashi (1970), Kobayashi, Matsui & Ishii (1970) .…”

Section: Transporting Ependymamentioning

confidence: 99%