Zur Natur der in menschlichem Plasma durch Pankreaskallikrein, Glaskontakt und S�urebehandlung gebildeten Kinine

Garbe, G.; Vogt, W.

doi:10.1007/bf00585364

Cited by 8 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the diagram concerning the two kininogenesis systems an important role is attributed to the Hageman enzyme (contact factor) which is the direct trigger of contact kallikrein activation as others (2, 3, 26,38,39,[50][51][52][53][64][65][66] and our own investigations (16,17,21) have shown. Our investigations demonstrated the parity of the behaviour of the Hageman factor activation and of contact kallikrein in plasma of a low fibrinolytic activity (17).…”

Section: Diagrammentioning

confidence: 57%

See 1 more Smart Citation

Contact and Plasmin Kinin-Forming Systems in the Blood

Buluk¹,

Czokało²,

Malofiejew³

1970

Thromb Haemost

View full text Add to dashboard Cite

SummaryBy means of preparations of two different kininogens, the existence of two kallikreins, postulated previously, that is one activated by the contact factor – contact kallikrein, and another by plasmin – plasmin kallikrein, has been confirmed.Stasis plasma or plasma from blood taken without stasis incubated at 37 ° C can be a source of contact kallikrein.It was found that modified plasma, that is plasma acidified to pH 2 and realkalized after 10 min, is suitable material for demonstrating that plasmin activates plasmin kallikrein. Plasmin kallikrein in the plasma has two substrates: kininogen – from which it releases kinins, and contact kallikrein which it inactivates. A diagram showing the activation of kinin-forming systems in the blood plasma is proposed.

show abstract

Section: Diagrammentioning

confidence: 57%

“…Vogt was the first (26,38,64,65) who drew attention to the fact that there were two different kallikreins which were active in two different kinin-forming systems. The investigations of Webster (67) , Paschina and co-workers (44) and Colman and coworkers (20) also suggested more than one kallikrein in plasma.…”

mentioning

confidence: 99%