“…Variation of the reaction parameters appears to have a considerable effect on the fluorescence characteristics and absorption spectra of the products (c/. 7,50,102,165,185,199,200,268); it was soon apparent that the reaction was not as simple as originally supposed and that variable mixtures of products were produced depending on the reaction conditions employed. Two-dimensional paper chromatography (after elimination of excess ethylenediamine, which interferes with the separation) has shown that the reaction between ethylenediamine and adrenaline gives eighteen products, while that with noradrenaline gives nineteen (184).…”