Zur Histopathogenese der sogenannten Myoblastenmyome

Nödl, F

doi:10.1007/bf00480544

Cited by 11 publications

(1 citation statement)

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“…Ihre neurogene Genese wurde von Feyrter in verschiedenen Arbeiten [5][6][7] eindrucksvoll dargelegt. Neurohistologische [10] und elektronenmikroskopische [3,4,12,14] Untersuchungen verschie dener Autoren bestätigen darüber hinaus die engen Beziehungen der Abrikossoffschen Tumoren mit dem von Feyrter [II] so genannten granulären Neurom (Neurinom).…”

Section: Seit Der Erstbeschreibung Gekörntzelliger Tumoren Der Zunge unclassified

Über neurogene granuläre Zellen und ihre Beziehungen zum sogenannten Myoblastenmyom

Altmeyer¹

1979

Dermatology

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A report on granular cells found in biopsy material is presented. Morphologically identical patterns were seen in a pigmentated granular ‘rankenneuroma’ and in a patient with a morphea of the tongue. The independent development of granular cells in tumorous and nontumorous tissue supports the idea that the so-called granular cell myoblastoma originates from degenerative alterations of Schwann cells.

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Section: Seit Der Erstbeschreibung Gekörntzelliger Tumoren Der Zunge unclassified

Über neurogene granuläre Zellen und ihre Beziehungen zum sogenannten Myoblastenmyom

Altmeyer¹

1979

Dermatology

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Multiple granular cell tumors (“myoblastomas”).Case report with electron microscopic observations and review of the literature

Moscovic

Azar

1967

Cancer

177

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A case of a 34‐year‐old woman with three histologically proven coincidental granular cell tumors is reported and documented with electron microscopic observations. The subject of multicentric occurrence of these rumors is reviewed in the literature and the available data and circumstances with a possible bearing on their nature are discussed. From the number of reviewed case reports (550) it appears that the occurrence of multiple granular cell tumors (36) is much more common (7 to 16%) than traditionally believed. Attention is drawn to their benign course. The precise histogenesis of these tumors and the chemical nature of the 160 to 240 Å vesicular units of the granules remain unknown. The authors conclude that the granular cells in this instance are of mesenchymal derivation and that the granules of these cells may represent the end result of an obscure metabolic alteration manifested by intracytoplasmic storage of protein and lipoid substances.

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