Zur Bestimmung des Gesamtschwefels in Geweben und Nahrungs stoffen

In one of the previous studies of this series it was shown that the cardiac and skeletal muscles of patients dying of congestive heart failure were abnormally poor in potassium, Harrison, PMlcher and Ewing (1930). The loss of-potassium from skeletal muscle appeared to be related to edema, as muscles which were not edematous contained normal amounts of potassium. Pieces of skeletal muscles removed during life contained less potassium when the patients were edematous than when they were edema free. It appears therefore that the presence of edema is an important cause of the loss of potassium in skeletal muscle. The present study was undertaken in an attempt to determine the cause of the loss of potassium from the cardiac muscle. METHODTissues were obtained at the postmortem table. Pieces of ventricular muscle weighing 5 to 20 grams were freed of fat, weighed and dried to constant weight at 105 to 110°C. One to two decigrams of the dried muscle were digested with nitric acid as described by Van Slyke (1924) for chloride determinations. The nitric acid was then driven off by evaporation, and the residue was freed of ammonia by boiling with excess sodium hydroxide. The mixture was then neutralized with sulphuric acid. Potassium was precipitated as the cobalti-

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“…These values are in fairly close agreement with those obtained for human subjects by Lematte, Boinot and Kahane (1928), and by Norn (1929).…”

Section: Resultssupporting

confidence: 92%

Studies in Congestive Heart Failure

Calhoun

Cullen²,

Clarke³

et al. 1930

J. Clin. Invest.

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“…As a matter of fact I have only been able to discover one analysis of the human heart which makes any pretension to a detailed series of determinations, by Lematte et al (1) and this apparently was only on one heart. These investigators determined the percentages of alkali and alkaline earth metals, phosphoric acid, iron, and dry residue, and reported their results in the form of the hydroxides of sodium, potassium, calcium, and magnesium.…”

mentioning

confidence: 97%

The Proportion of Certain Important Inorganic Constituents in the Dying Heart Muscle

Scott¹

1930

J. Clin. Invest.

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Careful survey of the literature does not reveal many examinations of the cardiac muscle for inorganic elements. As a matter of fact I have only been able to discover one analysis of the human heart which makes any pretension to a detailed series of determinations, by Lematte et al. (1) and this apparently was only on one heart. These investigators determined the percentages of alkali and alkaline earth metals, phosphoric acid, iron, and dry residue, and reported their results in the form of the hydroxides of sodium, potassium, calcium, and magnesium.

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Zur Bestimmung des Gesamtschwefels in Geweben und Nahrungs stoffen

Cited by 2 publications

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Studies in Congestive Heart Failure

Studies in Congestive Heart Failure

The Proportion of Certain Important Inorganic Constituents in the Dying Heart Muscle

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