Zum Beweis der Chromanstruktur des α-Tokopherols

John, W.; Dietzel, Ernst; Günther, Ph.; Emte, W.

doi:10.1007/bf01774259

Cited by 22 publications

(2 citation statements)

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“…Finally, the chroman ring as a constituent of α-tocopherol was confirmed with the help of UV spectra and other comparative model tests by Walter John at Göttingen University in Germany [30,31]. Furthermore, Walter John validated the chemical structure of α-tocopherolproposed by Fernholz and isolated ß-tocopherol simultaneously.…”

Section: The Discovery Of Vitamin E's Unique Physiological Function A...mentioning

confidence: 74%

A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition

Shastak,

Obermueller-Jevic,

Pelletier

2023

Agriculture

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Vitamin E, consisting of four tocopherols and four tocotrienols, with α-tocopherol as the most biologically active form, has a significant history in scientific research. It was first identified in the 1920s for its role in preventing neonatal mortality in rats. Over time, its chemical structure was elucidated, and its importance in the immune system, skin health, anti-inflammatory properties, and hormonal balance was revealed. Vitamin E production has evolved from natural sourcing to efficient synthesis with standardized potency units. Initially, animal studies focused on reproductive health and growth disorders, but later research highlighted vitamin E’s role in preventing encephalomalacia in domestic fowl and muscular dystrophy in various animals. Today, vitamin E is commonly used as a feed additive to enhance animal health and immune function. Despite substantial knowledge about its role in animal nutrition, several questions remain unanswered. Current research seeks to determine optimal supplementation levels, interactions with other nutrients, impacts on gene expression, cell signaling, and communication, as well as the effects of high dosages in livestock. Vitamin E continues to be a crucial component in improving animal health, and ongoing research aims to uncover its benefits and mechanisms of action further.

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