Zoster-like segmental presentation of lepromatous leprosy

Maroja, Maria de Fátima; Lima, Livia Lima de; Pereira, Priscilla Maria Rodrigues; Oliveira, Rosa Maria Libório de; Massone, Cesare

doi:10.47276/lr.81.3.224

Cited by 3 publications

(2 citation statements)

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“…Leprosy presents with a broad clinical and histopathological spectrum that is better correlated with the immunological response of the patient than with the initial bacillary invasion which is classically neurotropic. It has also been established that in anergic leprosy, a bilaterally symmetrical, distribution of hypopigmented macules, nodules or plaques are seen; 1 and while many unusual and protean manifestation of LL have been described, 2–5 a dermatomal presentation is decidedly uncommon. 4,5…”

Section: Discussionmentioning

confidence: 99%

“…The previous two cases reported were notably also of the multibacillary spectrum. 4,5 While LL is characterised by anergy and lesions are usually bilateral, a unilateral distribution led us initially to believe that the lesions were of a histoid pattern. A possible explanation is an initial borderline leprosy that had downgraded; however, biopsy findings were not supportive of this supposition.…”

Section: Discussionmentioning

confidence: 99%

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Zosteriform multidermatomal nodules and plaques in a case of lepromatous leprosy: an uncommon presentation

et al. 2020

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Leprosy is caused by the obligate intracellular organism Mycobacterium leprae which mainly affects the skin and nervous system. The course of the disease is determined by host immunity, it is thus believed that in lepromatous leprosy (LL), all manifestations are bilaterally symmetrical. This is because of the inability of the host to mount an adequate cell-mediated immune response, resulting in widespread haematogenous dissemination of bacilli. Varied manifestations of LL have been reported; however, a multidermatomal pattern of nodules is hitherto unreported and we suggest a hypothesis for its presentation.

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