Zonisamide in the Treatment of Binge-Eating Disorder

Sodium oxybate in the treatment of binge eating disorder: An open‐label, prospective study

“…55,56 The longitudinal analysis assessed the rate of change of each outcome variable measured at each visit during the treatment period (binge episodes, binge days, weight, BMI, CGI-S, YBOCS-BE, and MADRS). We used a model for the mean of the outcome variable that included a term for time.…”

Memantine in the treatment of binge eating disorder: An open‐label, prospective trial

“…33 The primary analysis for each outcome that was assessed at every visit (frequency of binges, frequency of binge days, BMI, weight, CGI-S, and YBOCS-BE) was a longitudinal repeated-measures random regression analysis, using modifications of analyses we used in previous placebo-controlled studies of binge eating disorder. 5,6,[9][10][11][12][32][33][34] This longitudinal analysis was our primary analysis and assessed the rate of change of each outcome measure during the treatment period. We used a model for the mean of the outcome variable that included a term for time.…”

“…These response categories have been used in previous pharmacologic treatment studies of binge eating disorder. [4][5][6][9][10][11][12]32,33 The following safety measures were assessed: adverse events, routine blood chemistry and hematology laboratory values, urinalysis, physical examination findings, and an electrocardiogram.…”

Feasibility and acceptability of CD‐ROM‐based cognitive‐behavioural treatment for binge‐eating disorder

“…Current treatment approaches include cognitivebehavioural therapy (CBT) and interpersonal psychotherapy (Agras et al, 1994(Agras et al, , 1995Agras, Telch, Arnow, Eldredge, & Marnell, 1997;Marcus, Wing, & Fairburn, 1995;Peterson et al, 1998;Smith, Marcus, & Kaye, 1992;Telch, Agras, Rossiter, Wilfley, & Kenardy, 1990;Wilfley et al, 1993), and pharmacotherapy (Hudson et al, 1998;McElroy et al, 2003;McElroy, Kotwal, Hudson, Nelson, & Keck, 2004;McElroy, Shapira et al, 2004). Although these approaches are moderately successful in the short term in reduction or elimination of binge eating, many individuals remain symptomatic post-treatment, CBT has not shown consistent effects on weight loss, and relapse remains a concern (Agras et al, 1994).…”