Zones of bimanual and unimanual preference within human primary sensorimotor cortex during object manipulation

Theorin, Anna; Johansson, Roland S.

doi:10.1016/j.neuroimage.2007.03.042

Cited by 31 publications

(29 citation statements)

References 104 publications

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“…Corresponding analyses for the unimanual trials failed to indicate a difference related to movement number. As reported previously, the steady-state performance was similar for all types of trials (Theorin and Johansson, 2007).…”

Section: Behavior During the Hand-selection Phasesupporting

confidence: 87%

“…Similarly, separate regressors modeled the different hold tasks (left-hand, right-hand, and bimanual grip). Results concerning the hold task and steady-state performance have been published previously (Theorin and Johansson, 2007). Therefore, these regressors represented states of no interest in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…Change in hand assignment parallels a midline shift of lateralized activity in distal hand muscles, corticospinal pathways, and primary sensorimotor cortex (SMC), and related cerebellar areas (Johansson et al, 2006). Consistent with a central role of left-hemisphere processes for righthanders in performing skilled manual actions (Geschwind, 1975;Leiguarda and Marsden, 2000;Schluter et al, 2001), a leftlateralized dorsal parietal-premotor network provides critical neural substrates of the implemented action representation regardless of prime actor (Theorin and Johansson, 2007).…”

Section: Introductionmentioning

confidence: 91%

“…All were right-handed (Oldfield, 1971). A detailed description of the experimental procedure and the apparatus can be found in previous reports that address other aspects of data obtained in the same functional magnetic resonance imaging (fMRI) experiments (Johansson et al, 2006;Theorin and Johansson, 2007). In short, the target-chasing task involved moving a cursor (filled circle, diameter of 0.2°visual angle) on a computer screen to hit, as fast as possible, successively displayed targets (open square, side of 0.8°).…”

Section: Participants Apparatus and General Proceduresmentioning

confidence: 99%

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Selection of Prime Actor in Humans during Bimanual Object Manipulation

Theorin¹,

Johansson²

2010

J. Neurosci.

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In bimanual object manipulation tasks, people flexibly assign one hand as a prime actor while the other assists. Little is known, however, about the neural mechanisms deciding the role assignment. We addressed this issue in a task in which participants moved a cursor to hit targets on a screen by applying precisely coupled symmetrical opposing linear and twist forces on a tool held freely between the hands. In trials presented in an unpredictable order, the action of either the left or the right hand was spatially congruent with the cursor movements, which automatically rendered the left or right hand the dominant actor, respectively. Functional magnetic resonance imaging indicated that the hand-selection process engaged prefrontal cortical areas belonging to an executive control network presumed critical for judgment and decision-making and to a salience network attributed to evaluation of utility of actions. Task initiation, which involved switching between task sets, had a superordinate role with reference to hand selection. Behavioral and brain imaging data indicated that participants initially expressed two competing action representations, matching either mapping rule, before selecting the appropriate one based on the consequences of the initial manual actions. We conclude that implicit processes engaging the prefrontal cortex reconcile selections among action representations that compete for the establishment of a dominant actor in bimanual object manipulation tasks. The representation selected is the one that optimizes performance by relying on the superior capacity of the brain to process spatial congruent, as opposed to noncongruent, mappings between manual actions and desired movement goals.

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Section: Behavior During the Hand-selection Phasesupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 91%

Section: Participants Apparatus and General Proceduresmentioning

confidence: 99%

See 2 more Smart Citations

Selection of Prime Actor in Humans during Bimanual Object Manipulation

Theorin¹,

Johansson²

2010

J. Neurosci.

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“…A recent fMRI study showed that the activity of the primary sensorimotor area, including S1 (BA 1), increased in the bimanual manipulation of an object (Theorin and Johansson, 2007). In the task, interactions between the hands should be transmitted via the object.…”

Section: Discussionmentioning

confidence: 99%

The “Cutaneous Rabbit” Hopping out of the Body

Miyazaki¹,

Hirashima²,

Nozaki³

2010

J. Neurosci.

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Rapid sequential taps delivered first to one location and then to another on the skin create the somatosensory illusion that the tapping is occurring at intermediate locations between the actual stimulus sites, as if a small rabbit were hopping along the skin from the first site to the second (called the "cutaneous rabbit"). Previous behavioral studies have attributed this illusion to the early unimodal somatosensory body map. A functional magnetic resonance imaging study recently confirmed the association of the illusion with somatotopic activity in the primary somatosensory cortex. Thus, the cutaneous rabbit illusion has been confined to one's own body. In the present paper, however, we show that the cutaneous rabbit can "hop out of the body" onto an external object held by the subject. We delivered rapid sequential taps to the left and right index fingers. When the subjects held a stick such that it was laid across the tips of their index fingers and received the taps via the stick, they reported sensing the illusory taps in the space between the actual stimulus locations (i.e., along the stick). This suggests that the cutaneous rabbit effect involves not only the intrinsic somatotopic representation but also the representation of the extended body schema that results from body-object interactions.

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Comparison of unilateral and bilateral complex finger tapping‐related activation in premotor and primary motor cortex

Horenstein

Lowe

Koenig

et al. 2008

Human Brain Mapping

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Sixteen healthy right-handed subjects performed a complex finger-tapping task that broadly activates the motor and premotor regions, including primary motor (M1), ventral premotor (PMv), and dorsal premotor (PMd) cortex. This task was performed with the right hand only, left hand only and both hands simultaneously. Behavioral performance and the possibility of mirror movements were controlled through the use of MRI-compatible gloves to monitor finger movements. Using spatially normalized ROIs from the Human Motor Area Template (HMAT), comparisons were made of the spatial extent and location of activation in the left and right motor regions between all three tasks. During unilateral right and left hand tapping, ipsilateral precentral gyrus activation occurred in all subjects, mainly in the PMv and PMd. Ipsilateral M1 activation was less consistent and shifted anteriorly within M1, towards the border of M1 and premotor cortex. Regions of ipsilateral activation were also activated during contralateral and bilateral tasks. Overall, 83%/70%/58% of the ipsilaterally activated voxels in M1/PMd/PMv were also activated during contralateral and bilateral tapping. The mean percent signal change of spatially overlapping activated voxels was similar in PMv and PMd between all three tasks. However, the mean percent signal change of spatially overlapping M1 activation was significantly less during ipsilateral tapping compared with contra- or bilateral tapping. Results suggest that the ipsilateral fMRI activation in unilateral motor tasks may not be inhibitory in nature, but rather may reflect part of a bilateral network involved in the planning and/or execution of tapping in the ipsilateral hand.

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Zones of bimanual and unimanual preference within human primary sensorimotor cortex during object manipulation

Cited by 31 publications

References 104 publications

Selection of Prime Actor in Humans during Bimanual Object Manipulation

Selection of Prime Actor in Humans during Bimanual Object Manipulation

The “Cutaneous Rabbit” Hopping out of the Body

Comparison of unilateral and bilateral complex finger tapping‐related activation in premotor and primary motor cortex

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