ZnO nanorods as immobilization layers for interdigitated capacitive immunosensors

Sanguino, P.; Monteiro, Tiago; Bhattacharyya, S. R.; Dias, C.J.; Igreja, Rui; Franco, Ricardo

doi:10.1016/j.snb.2014.06.141

Cited by 22 publications

(18 citation statements)

References 23 publications

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“…Due to their high surface/volume ratio, surface tailoring ability, novel electron transport properties and electronic conductance multifunctionality it is possible to successfully immobilize various types of biomolecules. Mostly nanorods (NRs) [36,38,40,43,45,47,48,53,56,74,82,86] and nanowires (NWs) [29,33,42,46,49,75,77,94] were used as a biosensor platform. Nanoparticles (NPs) [35,37,50,83,84,97,98], quantum dots [34,44], other low-dimentional structures [30,32,39,52,70,71,76,79,80,81,85,89,93,95,99] and thin films [31,51,72,73] ...…”

Section: Application Of Zno Nanostructures In Biosensorsmentioning

confidence: 99%

“…The covalent binding involves a cross-linking agent between ZnO surface and molecules of the bioselective layer, which provides a significant structure of the bioselective layer and improves the biorecognition [89,47,78,81,87,88].…”

Section: Covalent Binding Between Zno Surface and Biomoleculesmentioning

confidence: 99%

“…Amine (-NH2) and thiol (-SH2) groups are formed after treatment with aminosilanes and mercaptosilanes, respectively [47,89]. The direct immobilization of protein through the interaction between amine and carboxyl groups after APTES silanization of ZnO surface has been investigated as well [78,81].…”

Section: Silanizationmentioning

confidence: 99%

“…The direct immobilization of protein through the interaction between amine and carboxyl groups after APTES silanization of ZnO surface has been investigated as well [78,81]. In the case of thiol-based silanizated ZnO surface, one more step needed for a protein immobilization [47,89]. Sang et al provided the protein adsorption after washing the silanizated ZnO with disuccinimidyl suberate (DSS), solved in dimethyl sulfoxide (DMSO) [89].…”

Section: Silanizationmentioning

confidence: 99%

“…Nowadays, the most developed and used biosensor platforms are electrical [29,32,33,37,42,46,47,56,87] and electrochemical [16,30,31,38,39,55,88,90,[92][93][94]. Electrical in particular are based on their Field Effect Transistor (FET) platforms demonstrate high level of detection but require additional input of lithography and nanotechnology, what makes these devices more complex and expensive.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review

Tereshchenko

Bechelany

Viter

et al. 2016

Sensors and Actuators B: Chemical

273

206

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Section: Application Of Zno Nanostructures In Biosensorsmentioning

confidence: 99%

Section: Covalent Binding Between Zno Surface and Biomoleculesmentioning

confidence: 99%

Section: Silanizationmentioning

confidence: 99%

Section: Silanizationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review

Tereshchenko

Bechelany

Viter

et al. 2016

Sensors and Actuators B: Chemical

273

206

View full text Add to dashboard Cite

Effect of chemical immobilization of SDF-1α into muscle-derived scaffolds on angiogenesis and muscle progenitor recruitment

Rajabi

Baharvand

Ashtiani

et al. 2017

J Tissue Eng Regen Med

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The availability of three-dimensional bioactive scaffolds with enhanced angiogenic capacity that have the capability to recruit tissue specific resident progenitors is of great importance for the regeneration of impaired skeletal muscle. Here, we have investigated whether introduction of chemoattractant factors to tissue specific extracellular matrix promotes cellular behaviour in vitro as well as muscle progenitor recruitment and vascularization in vivo. We developed an interconnective macroporous sponge from decellularized skeletal muscle with maintained biochemical traits of the intact muscle. SDF-1α, a potent cell homing factor involved in muscle repair, was physically adsorbed or chemically immobilized in these muscle-derived sponges. The immobilized sponges showed significantly higher SDF-1α conjugation efficiency along with improved metabolism and infiltration of muscle-derived stem cells in vitro, and thus generated uniform cellular constructs. In vivo, femoral muscle implantation in rats revealed a negligible immune response in all scaffold groups. We observed enhanced engraftment, neovascularization, and infiltration of CXCR4 cells in the immobilized-SDF-1α sponge compared with nonimmobilized controls. Although Pax7 cells identified adjacent to the immobilized-SDF-1α implantation site, other factors appear to be necessary for efficient penetration of Pax7 cells into the sponge. These findings suggest that immobilization of cell homing factors via chemical mediators can result in recruitment of cells to the microenvironment with subsequent improvement in angiogenesis.

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New Trends in Antibody-Based Electrochemical Biosensors

Prodromidis

Economou

2017

Past, Present and Future Challenges of Biosensors and Bioanalytical Tools in Analytical Chemistry: A Tribute to Professor Marco

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ZnO nanorods as immobilization layers for interdigitated capacitive immunosensors

Cited by 22 publications

References 23 publications

Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review

Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review

Effect of chemical immobilization of SDF-1α into muscle-derived scaffolds on angiogenesis and muscle progenitor recruitment

New Trends in Antibody-Based Electrochemical Biosensors

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