“…A variety of biomaterials, including hydrogel, metal, and polyester, have been widely used in tissue engineering. Among them, hydrogels are characterized by weak mechanical strength and rapid degradation, making them insufficient to support tissue repair. , Metal materials have poor biocompatibility and are difficult to degrade. , Interestingly, polyesters such as poly(3-caprolactone) (PCL), poly(lactic acid) (PLA), and poly(1,8-octanediol- co -citrate) (POC) have the advantages of good biocompatibility, excellent mechanical properties, controllable degradation, and fatigue-resistance characteristics which are suitable for the preparation of scaffolds. ,, However, POC elastomers have poor bioactivity, and their degradation products have also been reported to lower local pH, triggering an inflammatory response. − This drawback could hinder their widespread application in tissue engineering. − Therefore, to address these issues, the combination of POC with glycine-modified nanoclay has been introduced for the first time.…”