Zinc supplementation of vitrification medium improves in vitro maturation and fertilization of oocytes derived from vitrified-warmed mouse ovaries

Geravandi, Shirin; Azadbakht, Mehri; Pourmoradi, Mahsa; Nowrouzi, Fatemeh

doi:10.1016/j.cryobiol.2016.12.007

Cited by 12 publications

(5 citation statements)

References 23 publications

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“…Improvements in cumulus-oocyte complex maturation, reduced apoptosis of cumulus cells, improved in vitro embryo production, and improved embryo development through the blastocyst stage have been reported in mice, cattle, pigs, and humans ( Gao et al, 2007 ; Anchordoquy et al, 2011 ; Menezo et al, 2011 ; Picco et al, 2012 ; Anchordoquy et al, 2014a , 2014b ; Jeon et al, 2014 ; Geravandi and Azadbakht, 2017 ; Geravandi et al, 2017 ; Dantas et al, 2019 ). Supplementing Cu-free maturation, fertilization, and culture media with 0.46 or 0.68 mg/L of Cu increased the percentage of embryos reaching the 8-cell stage, as well as rate of morula and blastocyst formation and decreased apoptosis ( Gao et al, 2007 ).…”

Section: Discussionmentioning

confidence: 99%

Impact of trace mineral source on beef replacement heifer growth, reproductive development, and biomarkers of maternal recognition of pregnancy and embryo survival

Perry

Perkins

Northrop

et al. 2021

Journal of Animal Science

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Trace minerals are known to play important roles in early embryo development. The study objective was to determine effects of trace mineral source on heifer reproductive performance. Beef heifers (n = 129) were randomly assigned to one of two treatments. From weaning through breeding, all heifers were individually fed a basal diet supplemented with Co, Cu, Mn, and Zn either from organic sources (COMP; Cu, Mn, and Zn amino acid complexes and Co glucoheptonate; Availa-4, Zinpro Corporation, Eden Prairie, MN) or inorganic sources (INORG; Cu, Mn, and Zn hydroxychlorides; Intellibond C, M, and Z, Micronutrients, Indianapolis, IN) and Co as CoSO4. Blood samples and a reproductive tract score (RTS) were collected to determine pubertal status. All animals were synchronized and artificially inseminated (AI). Pregnancy status was determined by lymphocyte gene expression, circulating concentrations of pregnancy associated glycoproteins (PAG), and by transrectal ultrasonography after AI. Embryonic loss was defined as when a previously pregnant animal was subsequently diagnosed not pregnant. Data were analyzed using the MIXED procedure in SAS. Puberty (P = 0.44), pelvic area (P = 0.74), RTS (P = 0.49), and estrus expression (P = 0.82) were not influenced by treatment. There was no effect of treatment (P = 0.37) or treatment by time (P = 0.19) on pregnancy, but there was a tendency (P = 0.13) for decreased embryonic loss among COMP heifers (27 ± 6%) compared to INORG heifers (38 ± 6%). There was a treatment by pregnancy status by time interaction (P < 0.01) on circulating PAG concentrations with PAG concentrations tending (P = 0.08) to be greater on d 25 among heifers in the COMP treatment compared to heifers in the INORG group. In summary, source of trace mineral did not affect puberty, RTS, pelvic area, or overall pregnancy success, but feeding complexed trace minerals tended to increase circulating PAG concentrations and embryo survival.

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Section: Discussionmentioning

confidence: 99%

Impact of trace mineral source on beef replacement heifer growth, reproductive development, and biomarkers of maternal recognition of pregnancy and embryo survival

Perry

Perkins

Northrop

et al. 2021

Journal of Animal Science

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“…Castillo-Martín et al (2014) found enhancement of survival rate and redox status of in vitro produced porcine blastocysts upon supplementing L-ascorbic acid. Additionally, zinc supplementation to vitrification medium improves oocyte maturation and fertilization in vitro (Geravandi et al, 2017). Antioxidant micronutrients can protect embryo cells from damage caused by free radicals and can protect the embryo from oxidative stress.…”

Section: Embryo Developmentmentioning

confidence: 99%

The Adjuvant Impacts of Antioxidant Micronutrients on Ovarian Follicle Development, Oocyte Maturation and Embryo Development of Mammalian Species: A Review

Mohammed,

Al-Suwaiegh,

Al-Gherair

et al. 2024

IJAR

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The antioxidant micronutrients refers to minerals (zinc, selenium and copper) and vitamins (A, C and E). Antioxidant micronutrients has been shown to play pivotal roles in development of ovarian follicle, maturation of oocytes and development of embryos, pregnancy and live birth. Antioxidant micronutrients supplemented to mammalian species and in vitro culture media were followed. Antioxidant micronutrients are involved in a variety of cellular processes, including protein synthesis, gene expression and cell signaling. They are cofactors for many enzymes involved in metabolism and cell growth. Early ovarian follicle development regulates through antioxidant micronutrients. Antioxidant micronutrients supplementation to the maturation and culture media could improve oocyte maturation and embryo development, leading to higher rates of pregnancy and live birth. Antioxidant micronutrients supplementation had been shown to reduce the risk of chromosomal abnormalities. Antioxidant micronutrients supplementation to vitrification medium of oocytes improves subsequent in vitro maturation and fertilization in vitro of oocytes. In conclusion, antioxidant micronutrients supplementation are promising supplements for improving the success of assisted reproductive technologies by optimizing the culture environment. This review is designed to discuss the progress in antioxidant micronutrients supplementation on development of ovarian follicle, maturation of oocytes and development of embryos, pregnancy and live birth.

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“…However, the addition of inappropriate hormone concentrations in vitro can still interfere with oocyte maturation, including disordered chromosomal arrangement and abnormal spindle organization, leading to abnormal embryonic development [73]. Optimizing the quality level of oocyte maturation after vitrification combined with in vitro maturation needs to be improved by adding supplements or relaxants, as reported by other researchers [74,75]. Adding various antioxidants to the media can also be a strategy for protecting oocytes from oxidative stress during in vitro maturation [76].…”

Section: Biobanking On Oocytesmentioning

confidence: 99%

Biobanking of Endangered Mammalian Gametes and Embryos: A Review

A. A. Muhammad Nur Kasman,

Ekayanti Mulyawati Kaiin2,

Hany Puspita Aryani

et al. 2023

J. Adv. Zool.

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The wealth of fauna resources has a strategic role in realizing the sovereignty and independence of the nation, so it needs to be preserved. Mammals contribute various ecological functions essential to human welfare, including sustaining energy flows and productivity and producing a different kind of biodiversity that is currently approaching extinction yet still exists. Animal biobanking is mostly focused on spermatozoa, oocytes, and embryos in various faunas, which is very relevant and an essential idea for producing healthy and sustainable populations. The quality of reproduction of local fauna with substantial economic value has also been increasingly degraded in recent years, so an accelerated effort in the field of conservation is needed, including integrating the latest technology with conservation efforts. However, the development of biobanking technology for endangered mammals still needs to be improved in its studies and innovations. The authors examine this issue since there is still information that has to be enhanced on the use of reproductive biotechnology techniques that center on the biobanking of animal gametes and embryos, particularly those of endangered mammals. This article provides information on the biobanking of sperm, oocytes, and embryos in endangered mammals.

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Zinc supplementation of vitrification medium improves in vitro maturation and fertilization of oocytes derived from vitrified-warmed mouse ovaries

Cited by 12 publications

References 23 publications

Impact of trace mineral source on beef replacement heifer growth, reproductive development, and biomarkers of maternal recognition of pregnancy and embryo survival

Impact of trace mineral source on beef replacement heifer growth, reproductive development, and biomarkers of maternal recognition of pregnancy and embryo survival

The Adjuvant Impacts of Antioxidant Micronutrients on Ovarian Follicle Development, Oocyte Maturation and Embryo Development of Mammalian Species: A Review

Biobanking of Endangered Mammalian Gametes and Embryos: A Review

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