Zinc supplement reduces allergic responses through modulating the p38 MAPK pathway activation in an allergic rhinitis mouse model

Shi, Qiangyou; Shen, Xueliang; Long, Chao; Mi, Zhipeng; Li, Yongchun; Ma, Ruixia

doi:10.1016/j.jtemb.2022.127094

Cited by 2 publications

(1 citation statement)

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“…170 Polaprezinc induces upregulation of osteogenic-related genes and enhances the osteogenic potential of human bone marrow-derived mesenchymal stem cells and the osteoclast differentiation potential of mouse bone marrowderived monocytes. 171 In addition to the cases discussed above, zinc has been used to treat several other diseases; for example, zinc supplementation can prevent otitis media, 172 acts as an anti-allergic and antiinflammatory agent, 173 as an adjunctive therapy to relieve inflammation and genital ulcers in patients with leukodystrophy, 174 treatment of skin diseases, and so forth. 175,176 Notably, although zinc citrate complexes have the potential to be additional instruments in the battle against cancer, they should be utilized cautiously due to potential toxicity on fibroblasts.…”

Section: Applications In Fortified Foodsmentioning

confidence: 99%

Dietary zinc supplements: beneficial health effects and application in food, medicine and animals

Shi,

Hao,

et al. 2024

J Sci Food Agric

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Zinc, a crucial trace element is vital for the growth and development of humans. It is frequently described as ‘the flower of life’ and ‘the source of intelligence’. Zinc supplements play a pivotal role in addressing zinc deficiency by serving as a vital source of this essential micronutrients, effectively replenishing depleted zinc levels in the body. In this paper, we first described the biological behavior of zinc in the human body and briefly described the physiological phenomena associated with zinc levels. The benefits and drawbacks of various zinc supplement forms are then discussed, with emphasis on the most recent zinc supplement formulations. Finally, the application of zinc supplements in food, medicine, and animal husbandry is further summarized. © 2024 Society of Chemical Industry.

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