Zinc phthalocyanine conjugated with the amino-terminal fragment of urokinase for tumor-targeting photodynamic therapy

Anode Interface Engineering and Architecture Design for High‐Performance Lithium–Sulfur Batteries

“…When the B content was only 20 wt%, the fibrillar network structure of the Li–B alloy was not maintained during the Li plating and stripping process, resulting in poor electrochemical performance. Zhang and co‐workers examined the 3D nanostructure of Li–B alloy . The 3D nanostructure provided a large specific area, low current density, and suppressed dendrite growth ( Figure a).…”

A real-time follow-up of photodynamic therapy during PET imaging

“…(4b), which in turn represents tissue blood volume (TBV). Radiotracer concentrations in blood and in plasma are interrelated and slightly vary with time [4], but we consider them as equivalent in this work where our interest is to compare different states. Alternatively, one can withdraw some 5 blood samples as a function of time through the PET measurement, measures whole blood and plasma concentrations of the radiotracer and obtains a conversion factor between whole blood and plasma curves.…”

“…In PET imaging, the cerebral activation in a single session is practiced for decades, and its imaging protocol resembles to the present study. The traditional therapies of cancer including surgery, radiotherapy and chemotherapy always generate adverse effects while PDT is more controllable by selectively acting on tumor sub-volumes and sparing normal tissues [4]. The action of the red light ( = 670 nm) allows a penetration till 10 mm, and the advantage of PDT is that it can be safely repeated in case of recurrence.…”

Therapeutics targeting the fibrinolytic system

“…First, we reported a method of uPARtargeted photodynamic therapy (PDT) that involved the conjugation of a photosensitizer (zinc phthalocyanine, ZnPc) with ATF ( Fig. 2a) 121 . Conjugation with ATF remarkably enhanced the antitumor specificity and efficacy of ZnPc in vitro and in vivo.…”