Zinc oxide nanoparticles incorporated in ultrathin layer silicate films and their photocatalytic properties

Szabó, Tamás; Németh, József; Dékány, Imre

doi:10.1016/j.colsurfa.2003.09.010

Cited by 105 publications

(49 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nanoparticles are making signifi cant contributions to the development of new approaches of drug delivery in cancer and can provide a platform for combined therapeutics with subsequent monitoring of response [1,2]. Progress in utilizing inorganic nanoparticles for biomedical applications has advanced rapidly due to the extensive amount of work done in the synthesis and modification of these particles [1].…”

Section: Introductionmentioning

confidence: 99%

Selective cytotoxic effect of ZnO nanoparticles on glioma cells

et al. 2009

View full text Add to dashboard Cite

In this study we examined the cytotoxic effect of ZnO nanoparticles on various human cancer and normal cells. We found that the ZnO nanoparticles exerted a cytotoxic effect on the human glioma cell lines A172, U87, LNZ308, LN18, and LN229, whereas no cytotoxic effect was observed on normal human astrocytes. Similarly, the ZnO nanoparticles induced cell death in breast and prostate cancer cell lines while no major effect was observed in the respective normal breast and prostate cell lines. Using the fl uorescent dye 2,7-dichlorofl uorescein diacetate, we found that treatment of the glioma cells with ZnO nanoparticles induced a large increase in the generation of reactive oxygen species (ROS) and treatment of the cells with N-acetyl cysteine decreased the cytotoxic effect of the ZnO nanoparticles. In contrast, a smaller effect on ROS generation was observed in the normal astrocytes. These results suggest that ZnO nanoparticles may be employed as a selective cytotoxic agent for the eradication of cancer cells.

show abstract

Section: Introductionmentioning

confidence: 99%

Selective cytotoxic effect of ZnO nanoparticles on glioma cells

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Progress in utilizing inorganic nanoparticles (NP) for biomedical applications has advanced rapidly as a result of the extensive amount of work done in the synthesis and fabrication of smart NP (Liong et al 2008). Among inorganic materials, metal oxide NPs are of special interest; especially zinc oxide (ZnO) which has photocatalytic property, photo-oxidizing ability against chemical and biological species (Szabo et al 2003). ZnO nanostructures are available in wide varieties, among them flower-like, snowflake-like, prism-like, prickly sphere-like and rod-like shapes have already been investigated (Jung et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Damage of lipopolysaccharides in outer cell membrane and production of ROS-mediated stress within bacteria makes nano zinc oxide a bactericidal agent

et al. 2014

View full text Add to dashboard Cite

Zinc oxide nanoparticle (ZNP) has been synthesized by microwave-assisted technique with the aid of a buffer solution. ZNP inhibited the growth of bacterial system Escherichia coli, even its multidrug-resistant counterpart as well. Systematic evaluation reveals that bioavailable crystalline ZNP damages the lipopolysaccharide layer from outer membrane (OM) of E. coli, subsequently damages the OM followed by inner membrane, enters within the cell and generates extensive reactive oxygen species-mediated damage. A series of biochemical, biophysical and molecular techniques have been used to reach the conclusion. We believe this work is expected to enlighten the detailed mode of action study in bacterial system.

show abstract

“…[4][5][6] In addition to its novel physical properties, [7][8][9] it belongs to a group of metal oxides that are characterized by their photocatalytic and photo-oxidizing ability against chemical and biological species. 10 ZnO is, therefore, recognized for its utility in biological applications as an antibacterial material. [11][12][13][14] Efforts have been focused on the synthesis and modification of ZnO particles for different applications.…”

Section: Introductionmentioning

confidence: 99%

High-energy ball milling technique for ZnO nanoparticles as antibacterial material

Salah¹,

Habib²,

Khan³

et al. 2011

IJN

221

107

View full text Add to dashboard Cite

Nanoparticles of zinc oxide (ZnO) are increasingly recognized for their utility in biological applications. In this study, the high-energy ball milling (HEBM) technique was used to produce nanoparticles of ZnO from its microcrystalline powder. Four samples were ball milled for 2, 10, 20, and 50 hours, respectively. The structural and optical modifications induced in the ‘as synthesized’ nanomaterials were determined by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscope (TEM), and photoluminescence emission spectra (PL). SEM and TEM results show a gradual decrease in particle size from around 600 to ∼30 nm, with increased milling time. The initial microstructures had random shapes, while the final shape became quite spherical. XRD analysis showed ZnO in a hexagonal structure, broadening in the diffracted peaks and going from larger to smaller particles along with a relaxation in the lattice constant c . The value of c was found to increase from 5.204 to 5.217 Å with a decrease in particle size (600 to ∼30 nm). PL result showed a new band at around 365 nm, whose intensity is found to increase as the particles size decreases. These remarkable structural and optical modifications induced in ZnO nanoparticles might prove useful for various applications. The increase in c value is an important factor for increasing the antibacterial effects of ZnO, suggesting that the HEBM technique is quite suitable for producing these nanoparticles for this purpose.

show abstract

Zinc oxide nanoparticles incorporated in ultrathin layer silicate films and their photocatalytic properties

Cited by 105 publications

References 42 publications

Selective cytotoxic effect of ZnO nanoparticles on glioma cells

Selective cytotoxic effect of ZnO nanoparticles on glioma cells

Damage of lipopolysaccharides in outer cell membrane and production of ROS-mediated stress within bacteria makes nano zinc oxide a bactericidal agent

High-energy ball milling technique for ZnO nanoparticles as antibacterial material

Contact Info

Product

Resources

About