Zinc-induced Cell Death in Rice (Oryza Sativa L.) Roots

Chang, Hsien Bing; Lin, Chung Wen; Huang, Hao

doi:10.1007/s10725-005-0162-0

Cited by 90 publications

(46 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To further confirm whether the DNA damage in maize was induced by • OH generation, sodium benzoate, an • OH scavenger, 40 was added to the exposure solution. No change in γ-H2AX foci level was found in the control without HBCD exposure ( Table 2).…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Diastereomer-Specific Uptake, Translocation, and Toxicity of Hexabromocyclododecane Diastereoisomers to Maize

Wang

Huang

et al. 2012

J. Agric. Food Chem.

View full text Add to dashboard Cite

Hexabromocyclododecane (HBCD), a brominated flame retardant, has become a ubiquitous contaminant due to its wide application, persistence, and toxicity. HBCD diastereoisomers have different physical and chemical properties and may differ in their bioaccumulation and toxicity in plants. Accumulation and toxicity of α-, β-, and γ-HBCDs in maize were investigated in the present study. The accumulation was in the order β-HBCD > α-HBCD > γ-HBCD in roots and β-HBCD > γ-HBCD > α-HBCD in shoots. Both the inhibitory effect of the diastereoisomers on the early development of maize and the intensities of hydroxyl radical and histone H2AX phosphorylation in maize exposed to 2 μg L −1 HBCD followed the order α-HBCD > β-HBCD > γ-HBCD, indicating the diastereomer-specific oxidative stress and DNA damage in maize. It was further confirmed that the generation of reactive oxygen species was one, but not the only, mechanism for DNA damage in maize exposed to HBCDs.

show abstract

Section: ■ Results and Discussionmentioning

confidence: 99%

Diastereomer-Specific Uptake, Translocation, and Toxicity of Hexabromocyclododecane Diastereoisomers to Maize

Wang

Huang

et al. 2012

J. Agric. Food Chem.

View full text Add to dashboard Cite

show abstract

“…Cell death (Figure 3) assayed by the Evans Blue staining method indicates disintegration of the plasma membrane caused by Al 3+ (Baker and Mock, 1994). The Evans Blue stain method has been shown to be a reliable measure of the PCD in rice seedlings subjected to Zn-stress (Chang et al, 2005). The involvement of signal transduction in ROS-mediated cell death or DNA damage so far has not been established.…”

Section: Discussionmentioning

confidence: 99%

Mitogen-activated protein kinase signal transduction and DNA repair network are involved in aluminum-induced DNA damage and adaptive response in root cells of Allium cepa L.

Panda

Achary

2014

Front. Plant Sci.

View full text Add to dashboard Cite

In the current study, we studied the role of signal transduction in aluminum (Al3+)-induced DNA damage and adaptive response in root cells of Allium cepa L. The root cells in planta were treated with Al3+ (800 μM) for 3 h without or with 2 h pre-treatment of inhibitors of mitogen-activated protein kinase (MAPK), and protein phosphatase. Also, root cells in planta were conditioned with Al3+ (10 μM) for 2 h and then subjected to genotoxic challenge of ethyl methane sulfonate (EMS; 5 mM) for 3 h without or with the pre-treatment of the aforementioned inhibitors as well as the inhibitors of translation, transcription, DNA replication and repair. At the end of treatments, roots cells were assayed for cell death and/or DNA damage. The results revealed that Al3+ (800 μM)-induced significant DNA damage and cell death. On the other hand, conditioning with low dose of Al3+ induced adaptive response conferring protection of root cells from genotoxic stress caused by EMS-challenge. Pre-treatment of roots cells with the chosen inhibitors prior to Al3+-conditioning prevented or reduced the adaptive response to EMS genotoxicity. The results of this study suggested the involvement of MAPK and DNA repair network underlying Al-induced DNA damage and adaptive response to genotoxic stress in root cells of A. cepa.

show abstract

“…: copper is a cofactor in enzymes such as Cu-SOD, laccase and plastocyanin, participant in cell wall metabolism and stress response, and also acts as component of the electron transport chain [6]. Zinc is an enzyme cofactor in electron transport and antioxidant metabolism, and also a component of transcription factors [7].…”

mentioning

confidence: 99%

Direct analysis of elemental biodistribution in pea seedlings by LA-ICP-MS, EDX and confocal microscopy: Imaging and quantification

Hańć

Małecka

Kutrowska

et al. 2016

Microchemical Journal

View full text Add to dashboard Cite

Zinc-induced Cell Death in Rice (Oryza Sativa L.) Roots

Cited by 90 publications

References 35 publications

Diastereomer-Specific Uptake, Translocation, and Toxicity of Hexabromocyclododecane Diastereoisomers to Maize

Diastereomer-Specific Uptake, Translocation, and Toxicity of Hexabromocyclododecane Diastereoisomers to Maize

Mitogen-activated protein kinase signal transduction and DNA repair network are involved in aluminum-induced DNA damage and adaptive response in root cells of Allium cepa L.

Direct analysis of elemental biodistribution in pea seedlings by LA-ICP-MS, EDX and confocal microscopy: Imaging and quantification

Contact Info

Product

Resources

About