Zinc: Growth, development, and function

Sandstead, Harold H.

doi:10.1002/(sici)1520-670x(2000)13:1<41::aid-jtra6>3.0.co;2-g

Cited by 13 publications

(5 citation statements)

References 86 publications

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“…Zinc concentrations in serum, blood cells and hair decrease with severe zinc de®ciency. Children are particularly vulnerable to zinc de®ciency during the periods of rapid growth and development such as infancy and adolescence (Brown et al 1998, Prasad 1998, Sandstead 2000.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of zinc status, food products' frequency intake and food habits of 11-year-old healthy children

Schlegel-Zawadzka¹,

Zachwieja²,

Huzior-Baajewicz³

et al. 2002

Food Additives and Contaminants

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Children are particularly vulnerable to zinc (Zn) deficiency during periods of rapid growth and development such as infancy and adolescence. The aim was to find the relationship between food frequency, intake, food habits and zinc status in 11-year-old healthy children from southern Poland. The study group comprised children (n = 157) in the age range 11.0 +/- 0.4 years. The level of Zn in serum, erythrocytes and hair samples was measured using atomic absorption spectrophotometry. The parents of children examined completed a special food frequency questionnaire. The Zn concentration in hair (boys 182.98 +/- 65.63 microg x g(-1), n = 78; girls 203.82 +/- 39.80 microg x g(-1), n = 79; p = 0.0171), erythrocytes (8.60 +/- 2.76 mg x l(-1), n = 50) and blood serum (0.79 +/- 0.15 mg x l(-1)) correlated significantly (p < 0.05) with frequency intake of different products (hair: meat, rolls, fruit juices without additives, brawn, pate, barley, black pudding, fish canned, chips, margarine used for cooking, bacon; erythrocytes: fruits, matured cheese, dishes of meal, white cottage cheese, fruit juices without additives, cakes and cakes with cream, margarine used for bread spread; blood serum: bread, fruits, milk, kefir, yoghurt). The relationship of the Zn amount in food products, food frequency intake and the concentration in different healthy children tissues is influenced by many internal and external factors.

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Section: Introductionmentioning

confidence: 99%

Comparative analysis of zinc status, food products' frequency intake and food habits of 11-year-old healthy children

Schlegel-Zawadzka¹,

Zachwieja²,

Huzior-Baajewicz³

et al. 2002

Food Additives and Contaminants

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“…No adverse effect was encountered in Bufo arenarum embryos exposed to a concentration of up to 130 mg/l Zn 2+ . In studies conducted, beneficial effects of Zn 2+ on amphibian embryos were found to be a reduction in the rate of spontaneous anomalies and malformations, and protection against the retarded growth and development and death due to metals like Cd 2+ , Pb 2+ , Al 2+ , Hg 2+ , and Cu 2+ (Rink and Gabriel, 2001, Sandstead, 2000, Falchuk, 1998a, Pasky et al, 1996.…”

Section: Discussionmentioning

confidence: 99%

Effects of Specific Dosages of Magnesium and Zinc on the Teratogenicity of Cadmium, Nickel, and Cobalt in Xenopus Embryos, as Assessed by the Fetax Test

2007

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The objective of this study was to determine if exposure to divalent cations, Cd(2+), Ni(2+), and Co(2+) would lead to malformations in Xenopus laevis embryos, and whether addition of Mg(2+) and Zn(2+); separately and in combination, would reduce their toxicity and teratogenicity on the embryos of Xenopus laevis as assessed by 96-h FETAX tests. Results indicate that exposure to Cd(2+), Ni(2+) or Co(2+) lead to an increase in toxicity and teratogenicity in embryos, whereas Mg(2+), Zn(2+), or a combination of them reduced the toxic and teratogenic effects of these divalent cations. Modulation of Cd(2+), Ni(2+) or Co(2+) toxicity and teratogenicity by Mg(2+) and Zn(2+), varied with the metal. Zn(2+) was observed to be a better suppressor of Co(2+) toxicity and teratogenicity than Mg(2+). In contrast, Ni(2+), and Cd(2+) teratogenicity was reduced more prominently by Mg(2+). On the other hand, combination of Mg(2+) and Zn(2+) showed potentialization effect on all divalent cation toxicity and teratogenicity. We concluded that Mg(2+) and Zn(2+) reduced the toxicity and teratogenicity of Cd(2+), Ni(2+), Co(2+).

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“…[1][2][3][4] The deficiency of Zn 2+ ions in the brain and pancreas may result in various disorders such as Parkinson's disease, epilepsy, and certain cancers. 5,6 However, an excess dose of zinc can cause several health problems such as superficial skin diseases, prostate cancer, diabetes, and brain diseases. 7,8 Supra-optimal zinc concentrations in soil can cause toxicity effects on most of the plants, for instance the inhibition of root elongation and shoot growth.…”

Section: Introductionmentioning

confidence: 99%

“…4.12 (t, J=7.6 Hz, 4H, OCH2-), 6.14 (d, J=9 6. Hz, 2H, Ar-H), 6.76 (d, J=9.2 Hz, 2H, Ar-H), 7.34 (d, J=8.8 Hz, 2H, Ar-H), 7.37 (s, 4H, Ar-H), 7.45 (s, 4H, Ar-H), 7.56 (d, J=9.6 Hz, 2H, Ar-H), 8.85 (s, 2H, CH=N), 14.62 (s, 2H, OH); 13 C NMR (CDCl3, 500 MHz), δ (ppm): 31.42, 31.48, 34.40, 34.44, 55.32, 65.57, 66.17, 70.16, 71.40, 73.51, 105.60, 108.83 , 111.15 , 116.31, 126.44, 127.07, 127.74, 127.84, 132.40, 143.93, 146.87, 146.91, 155.01, 155.13, 156.46, 160.05, 160.27, 169.23; MALDI-TOF MS: m/z 1347.962 [M+K] + .…”

mentioning

confidence: 99%

A multichannel thiacalix[4]arene-based fluorescent chemosensor for Zn²⁺, F⁻ ions and imaging of living cells

Ran

Yuan

Yue

et al. 2015

Supramolecular Chemistry

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The fluorescent sensor 3 based on the 1,3-alternate conformation of thiacalix[4]arene bearing the coumarin fluorophore via an imino group has been synthesized. The sensing properties were evaluated in terms of a colorimetric and fluorescence sensor for Zn 2+ and F -. High selectivity and excellent sensitivity were exihibited, and "off-on" optical behavior in different media was observed. Changes were all visible to the naked eye, whilst the presence of the Zn 2+ and Finduces fluorescence enhancement and the formation of a 1:1 complex with sensor 3. In addition, the sensor 3 has low cytotoxicity and good cell permeability, and can readily be employed for assessing the change of intracellular Zn 2+ and Flevels.

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Zinc: Growth, development, and function

Cited by 13 publications

References 86 publications

Comparative analysis of zinc status, food products' frequency intake and food habits of 11-year-old healthy children

Comparative analysis of zinc status, food products' frequency intake and food habits of 11-year-old healthy children

Effects of Specific Dosages of Magnesium and Zinc on the Teratogenicity of Cadmium, Nickel, and Cobalt in Xenopus Embryos, as Assessed by the Fetax Test

A multichannel thiacalix[4]arene-based fluorescent chemosensor for Zn²⁺, F⁻ ions and imaging of living cells

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Zinc: Growth, development, and function

Cited by 13 publications

References 86 publications

Comparative analysis of zinc status, food products' frequency intake and food habits of 11-year-old healthy children

Comparative analysis of zinc status, food products' frequency intake and food habits of 11-year-old healthy children

Effects of Specific Dosages of Magnesium and Zinc on the Teratogenicity of Cadmium, Nickel, and Cobalt in Xenopus Embryos, as Assessed by the Fetax Test

A multichannel thiacalix[4]arene-based fluorescent chemosensor for Zn2+, F− ions and imaging of living cells

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Product

Resources

About

A multichannel thiacalix[4]arene-based fluorescent chemosensor for Zn²⁺, F⁻ ions and imaging of living cells