Zinc-doped hydroxyapatite and graphene oxide composites for bone and teeth implants: a theoretical understanding

Abstract

Recently, bone and teeth implants have relied on Hydroxyapatite(HA) benefits to mediate bone restoration, but its weak antibacterial and mechanical properties limit its usage. Research to address these properties has...

Injectable gelatin microspheres for osteomyelitis treatment: osteogenic and anti-inflammatory effect

“…With the increase of n-HA content, the protein adsorption capacity of the composite microspheres significantly increased. 16 The architecture of n-HA can offer biophysical information for the adjustment of cell behaviors (e.g., cell attachment, spreading, proliferation, or differentiation) and the subsequent process of osteogenesis for bone regeneration. 17 Previously, we reported the preparation of gelatin/nanohydroxyapatite (Gel/n-HA) (10 wt%) composite microspheres using a water-in-oil emulsification process and subsequent crosslinking with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC).…”

“…With the increase of n-HA content, the protein adsorption capacity of the composite microspheres significantly increased. 16 The architecture of n-HA can offer biophysical information for the adjustment of cell behaviors ( e.g. , cell attachment, spreading, proliferation, or differentiation) and the subsequent process of osteogenesis for bone regeneration.…”