Zinc content of human cancellous bone

Em, Alhava; Olkkonen, H.; Puittinen, J.; Vm, Nokso-koivisto

doi:10.3109/17453677708985102

Cited by 58 publications

(17 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, both cortical and trabecular bone showed an age-related reduction in the ratio of calcium to zinc and magnesium to zinc [39]. Similar changes in trabecular bone magnesium and zinc content, as well as calcium/zinc and magnesium/zinc ratios in cortical and trabecular bone have been reported with advancing age in men and women [40][41][42].…”

Section: Age-related Changes In Bone Masssupporting

confidence: 49%

Nonhuman Primate Models of Skeletal and Reproductive Aging

Black

Lane²

2002

Gerontology

View full text Add to dashboard Cite

Background: Bone loss, osteoarthritis (OA) and age-related changes in reproduction are some of the most apparent and troubling results of advancing age in the human population. The significance of these changes underscores the need for developing appropriate animal models to study aging of bone and the reproductive system. Objective: This review surveys the literature regarding the current state of nonhuman primates (NHP) as models for skeletal and reproductive aging in humans. Results: Several species of NHP exhibit age-related bone loss as well as changes in the mineral content and architecture of bone that are similar to those reported in humans. In addition, since aged females of some species of NHP exhibit cessation of menses and serum hormone profiles consistent with those described in peri- and premenopausal women, they provide useful models of postmenopausal bone loss. Sensitivity to surgical estrogen depletion and hormone replacement has also been demonstrated in female NHP. Spontaneous development of degenerative arthritis, analogous to humans in age at onset, joint involvement and histologic changes, suggest that NHP are suitable for the study of human OA. Many similarities exist between female NHPs and women in age-related changes in reproductive function including hormone concentrations, menstrual cycling, fertility and the development of endometriosis. Changes in male sexual behavior and fertility with age are also comparable in men and male NHP. Conclusions: Genetic similarity, long lives and similar reproductive endocrinology suggest that NHPs are likely candidates as models of skeletal and reproductive aging in humans. Current data confirm that several species of NHP exhibit changes in bone and reproduction that are comparable to those known to occur in humans.

show abstract

Section: Age-related Changes In Bone Masssupporting

confidence: 49%

Nonhuman Primate Models of Skeletal and Reproductive Aging

Black

Lane²

2002

Gerontology

View full text Add to dashboard Cite

show abstract

“…In 90% of patients, an episode of LBP typically subsides within 2 to 4 weeks [2–4]. However, the recurrence rate of LBP is alarmingly high at an estimated rate of 60–80% [5, 6]. A rising focus in research and rehabilitation is on treatment classification of nonspecific LBP into smaller subgroups (manual therapy, specific exercises, traction, and stabilization) so that more specific rehabilitative techniques can be prescribed [7, 8].…”

Section: Introductionmentioning

confidence: 99%

No Difference in Transverse Abdominis Activation Ratio between Healthy and Asymptomatic Low Back Pain Patients during Therapeutic Exercise

Gorbet

Selkow

Hart

et al. 2010

Rehabilitation Research and Practice

View full text Add to dashboard Cite

Dysfunction of the transverse abdominis (TrA) has been associated with LBP. Several therapeutic exercises are prescribed to help target the TrA. Rehabilitative ultrasound imaging (RUSI) is used to capture activation of the TrA during exercise. The purpose was to examine TrA activation during the ADIM and quadruped exercises between healthy and nonsymptomatic LBP patients. We instructed the subjects how to perform the exercises and measured muscle thickness of the TrA at rest and during the exercises using RUSI. This allowed us to calculate TrA activation ratio during these exercises. We found no significant differences between activation ratios of the two groups during either exercise; however TrA activation during the ADIM was higher than the quadruped exercise. These exercises were capable of activating the TrA, which may be in part due to the verbal instruction they received. These exercises could be used during prevention or rehabilitation programs, since the TrA is activated.

show abstract

“…One sample was fixed in 40 per cent ethyl alcohol and the other sample was treated with sodium hypochlorite, hydrogen peroxide and xylene to remove bone marrow and fat as described in detail by Alhava et al (1977).…”

Section: Bone Materialsmentioning

confidence: 99%