Zinc and infant nutrition

Ackland, M. Leigh; Michalczyk, Agnes

doi:10.1016/j.abb.2016.06.011

Cited by 101 publications

(86 citation statements)

References 142 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Maternal deficiencies in trace minerals during pregnancy primarily impact the fetus, and many of the most detrimental effects can be seen during the first trimester, before the pregnancy is known. Trace minerals have a role in early fetal organ system development as important players in cell growth and differentiation [70,73,99,100]. This effect is seen most prominently in growth of the vascular system, kidneys and pancreas, and deficiency may predispose the child to cardiometabolic diseases as an adult [70].…”

Section: Trace Mineralsmentioning

confidence: 99%

Nutritional Gaps and Supplementation in the First 1000 Days

Korczak²,

et al. 2019

View full text Add to dashboard Cite

Optimized nutrition during the first 1000 days (from conception through the 2nd birthday) is critical for healthy development and a healthy life for the newborn. Pregnancy and the postpartum period are accompanied by physiological changes, increased energy needs, and changing requirements in the nutrients critical for optimal growth and development. Infants and toddlers also experience physiological changes and have specific nutritional needs. Food and nutrition experts can provide women of childbearing age with adequate dietary advice to optimize nutrition, as well as guidance on selecting appropriate dietary supplements. Considering the approaching 2020–2025 Dietary Guidelines for Americans (DGA) will be making specific recommendations for children, it is important to provide accurate scientific information to support health influencers in the field of nutrition. The purpose of this review is to summarize the nutrition and supplementation literature for the first 1000 days; to highlight nutritional and knowledge gaps; and to educate nutrition influencers to provide thoughtful guidance to mothers and families. Optimal nutrition during pregnancy through early childhood is critical for supporting a healthy life. Nutrition influencers, such as dietitians, obstetricians/gynecologists, and other relevant health professionals, should continue guiding supplement and food intake and work closely with expectant families and nutrition gatekeepers.

show abstract

Section: Trace Mineralsmentioning

confidence: 99%

Nutritional Gaps and Supplementation in the First 1000 Days

Korczak²,

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The evolution of these molecules during sprouting is mainly due to enzymatic mechanisms aiming to provide the embryo with nutrients . The increase in lipid and protein contents might be related to an effect of zinc on lipases and proteases: In fact, zinc plays a key role in structural and catalytic functions of numerous enzymes . In addition, it is involved in several enzymatic reactions .…”

Section: Resultsmentioning

confidence: 99%

“…47 The increase in lipid and protein contents might be related to an effect of zinc on lipases and proteases: In fact, zinc plays a key role in structural and catalytic functions of numerous enzymes. 17 In addition, it is involved in several enzymatic reactions. 13 Still, levels of reducing sugars were lower in zinc-treated sprouted seeds than in control ones.…”

Section: Effect Of Zinc Disinfection Treatment and Sprouting On Nutrimentioning

confidence: 99%

“…14 From a metabolic point of view, zinc reduces oxidative stress. 17 It is also involved in more than 300 enzymatic reactions as a cofactor 13,16 and regulates structural functions, gene expression, cell division and organ development, neuronal transmission, immune response and cognitive functions. 16,17 Recommended amounts range between 8 and 11 mg day −1 for men and women respectively.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Zinc fortification as a tool for improving sprout hygienic and nutritional quality: a factorial design approach

et al. 2019

View full text Add to dashboard Cite

Background Sprouting is known to improve cereal and pulse nutritional properties. However, several outbreaks of illness have been reported after raw sprout consumption. This research aimed to improve wheat sprout hygienic properties through the use of zinc diacetate. Sprouting conditions (sprouting temperature, soaking time and zinc diacetate solution concentration) were optimized to decrease total plate count, coliforms, and molds and yeasts using a factorial design approach and a desirability function. Results Based on the responses, the effects of variables were calculated and the interactions between them were determined. Optimal conditions were defined as follows: sprouting temperature 18 °C, soaking time 0.66 h and zinc diacetate concentration 400 mg L−1. These conditions led to the elimination of coliforms and a decrease in total flora count by 2 log. Interestingly, zinc sprouting increased the zinc content of sprouts and improved their nutritional properties. Conclusion Results showed that the use of zinc solution is a useful tool to improve sprout hygienic and nutritional properties. © 2019 Society of Chemical Industry

show abstract

“…Presence of infections leads to inflammatory response and subsequent stress hyperglycaemia [14]. Vitamin A and Zinc deficiencies which usually occur in children with severe malnutrition can cause oral sores [24,25]. Children with micronutrient deficiencies also have compromised immunity which makes them susceptible to stress hyperglycaemia.…”

Section: Stress Hyperglycaemia Among Children With Oral Soresmentioning

confidence: 99%

Prevalence and outcome of stress hyperglycaemia among severely malnourished children admitted to Mulago referral and teaching hospital in Kampala, Uganda

et al. 2018

View full text Add to dashboard Cite

Background: Stress hyperglycaemia is a transient increase in blood glucose level during stressful events and is common in critically ill children. Several studies have demonstrated increased risk of mortality in these children. There is paucity of information on this subject in sub Saharan Africa. The aim of this study was to describe the prevalence, outcome and factors associated with stress hyperglycaemia among children with severe acute malnutrition (SAM) admitted to the Mwanamugimu nutrition unit of Mulago hospital in Uganda. Methods: This study was conducted from August 2015 to March 2016 at the Mwanamugimu nutrition unit of Mulago hospital among severely malnourished children aged 1 to 60 months. Random blood sugar levels were measured. Stress hyperglycaemia was considered as a random blood sugar > 150 mg/dl. The final outcome was ascertained at death or discharge. Statistical analysis was done using the Chi square test and logistic regression. Results: Two hundred and thirty-five children were enrolled of whom 50% were girls. The median age was 5.1 months (range 1-60 months). Stress hyperglycaemia was present in 16.6% of the 235 participants. Several factors were significantly associated with stress hyperglycaemia at bivariate analysis; but on logistic regression, only presence of oral sores was associated with stress hyperglycaemia: (Odds ratio 2.61; 95% CI 1.02-6.65). Mortality was higher among children with stress hyperglycaemia (56.4%) compared to (12.8%) in the nonhyperglycaemic group: OR 8.75; 95% CI 4.09-18.70). Conclusion: The prevalence of stress hyperglycaemia was 16.6% and was associated with high mortality. It is important to monitor blood glucose levels of severely malnourished children. Hitherto, the main concern among severely malnourished children has been hypoglycaemia. Innovative ways of preventing and managing stress hyperglycaemia among these children are urgently needed.

show abstract

Zinc and infant nutrition

Cited by 101 publications

References 142 publications

Nutritional Gaps and Supplementation in the First 1000 Days

Nutritional Gaps and Supplementation in the First 1000 Days

Zinc fortification as a tool for improving sprout hygienic and nutritional quality: a factorial design approach

Prevalence and outcome of stress hyperglycaemia among severely malnourished children admitted to Mulago referral and teaching hospital in Kampala, Uganda

Contact Info

Product

Resources

About