“…Many studies on the pathogenesis of ZIKV have focussed on the proliferation, survival and differentiation of CNS neural precursors; the use of iPS derived human cells conferring species-specific relevance, in some studies [4, 15, 27, 28, 41, 46, 49, 64, 68, 70, 91, 99]. However, it is not currently possible, using human cells, to generate in vitro models of the relatively more mature nervous systems, comprising differentiated neurones and glia and myelinated nerve fibres.…”