Zika virus epidemic in Puerto Rico: Health justice too long delayed

Rodríguez-Díaz, Carlos E.; Garriga-López, Adriana; Malavé-Rivera, Souhail M.; Vargas‐Molina, Ricardo L.

doi:10.1016/j.ijid.2017.07.017

Cited by 21 publications

(13 citation statements)

References 22 publications

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“…Racial/ethnic minority populations have historically borne a disproportionate burden of illness, hospitalization, and death during public health emergencies, including the 2009 H1N1 influenza pandemic and the Zika virus epidemic ( 1 – 4 ). This disproportionate burden is due to a higher level of social vulnerability — “individual and community characteristics that affect capacities to anticipate, confront, repair, and recover from the effects of a disaster” — among racial/ethnic minority populations than among non-Hispanic White populations ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Community Engagement of African Americans in the Era of COVID-19: Considerations, Challenges, Implications, and Recommendations for Public Health

Akintobi

Jacobs²,

Sabbs

et al. 2020

Prev. Chronic Dis.

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What is already known on this topic? African Americans are more likely to contract coronavirus disease 2019 (COVID-19), be hospitalized for it, and die of the disease when compared with other racial/ethnic groups. Psychosocial, sociocultural, and environmental vulnerabilities, compounded by preexisting health conditions, exacerbate this health disparity. What is added by this report? This report adds to an understanding of the interconnected historical, policy, clinical, and community factors associated with pandemic risk, which underpin community-based participatory research approaches to advance the art and science of community engagement among African Americans in the COVID-19 era. What are the implications for public health practice? When considered together, the factors detailed in this commentary create opportunities for new approaches to intentionally engage socially vulnerable African Americans. The proposed response strategies will proactively prepare public health leaders for the next pandemic and advance community leadership toward health equity.

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Section: Introductionmentioning

confidence: 99%

Community Engagement of African Americans in the Era of COVID-19: Considerations, Challenges, Implications, and Recommendations for Public Health

Akintobi

Jacobs²,

Sabbs

et al. 2020

Prev. Chronic Dis.

View full text Add to dashboard Cite

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“…However, G010 was significantly different from K048 and K054, in that it has no ZIKV-induced neuronal reduction and innate immune genes upregulation [ 15 ]. Beginning in 2016, Puerto Rico witnessed the most negative consequences of ZIKV infection with the first birth of a ZIKV-related microcephaly baby in the U.S. [ 34 ]. Little is known about whether different strains of the Asian lineage ZIKV will have different effects on neurogenesis, although several studies have pointed out the ZIKV of the Asian and African lineage differ in their impact on neural development and antiviral immune responses [ 35 – 40 ].…”

Section: Resultsmentioning

confidence: 99%

Inhibition of innate immune response ameliorates Zika virus-induced neurogenesis deficit in human neural stem cells

Gao

Shan

et al. 2021

PLoS Negl Trop Dis

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Global Zika virus (ZIKV) outbreaks and their strong link to microcephaly have raised major public health concerns. ZIKV has been reported to affect the innate immune responses in neural stem/progenitor cells (NS/PCs). However, it is unclear how these immune factors affect neurogenesis. In this study, we used Asian-American lineage ZIKV strain PRVABC59 to infect primary human NS/PCs originally derived from fetal brains. We found that ZIKV overactivated key molecules in the innate immune pathways to impair neurogenesis in a cell stage-dependent manner. Inhibiting the overactivated innate immune responses ameliorated ZIKV-induced neurogenesis reduction. This study thus suggests that orchestrating the host innate immune responses in NS/PCs after ZIKV infection could be promising therapeutic approach to attenuate ZIKV-associated neuropathology.

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“…Some complexities here necessitate a pause. Considering the difficulty Puerto Rican women face in procuring the kind of contraception they might desire and the cultural setting of abstinence‐only sexual education in which girls are socially punished for expressions of sexual agency (Rodríguez‐Díaz et al, 2017), the expansion of access to contraception is a good thing. However, the question of reproductive “choice” can never be extracted from the political economic and biopolitical conditions that enfold it.…”

Section: Models and Metrics Of Reproductive Cost‐effectivenessmentioning

confidence: 99%

For the sake of the child: The economisation of reproduction in the Zika public health emergency

Patchin

2020

Trans Inst British Geog

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Feminist work on population governance has tracked its racial dynamics, its varied attempts to expunge the poor from the future, and its violent wresting of control over reproduction away from women. Attention has recently turned to “economised” understandings of possible and proto‐life that take the aggregate reproductivity of certain groups of women and girls as a means of shaping economic futures, which emerged as the dominant form of population governance during the Cold War. Underexplored in this incisive body of work, however, is the relationship between the reproductive body and social reproduction. This paper advances feminist work on adjudications of life worth in government policy and scientific expertise, and critical political economic work on global health governance, by exploring experiments in family planning. I do this through a discussion of the Zika virus, the recent re‐emergence of which was framed as an economic problem: experts “priced” a single case of microcephaly at US$10 million or more across a lifetime. Specifically, I examine a programme of contraceptive provision to women in Puerto Rico as part of the public health emergency, which I show to have possible eugenic effects. I argue that in the global politics of public and reproductive health, relatively new neoliberal health metrics have joined up with eugenicist impulses to value life according to future economic contributions. Such valuations of life focalise the reproductive body while abandoning the social reproductive body. The relationship between reproductive labour and social reproduction warrants further scrutiny, for as we careen through uncertain ecological futures, and as discourses about limited Earth for humans amid environmental crisis and limited funding for future children thicken, the reproductivity of certain women and girls is being tinkered with by experts, governments, and private institutions in new ways.

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Zika virus epidemic in Puerto Rico: Health justice too long delayed

Cited by 21 publications

References 22 publications

Community Engagement of African Americans in the Era of COVID-19: Considerations, Challenges, Implications, and Recommendations for Public Health

Community Engagement of African Americans in the Era of COVID-19: Considerations, Challenges, Implications, and Recommendations for Public Health

Inhibition of innate immune response ameliorates Zika virus-induced neurogenesis deficit in human neural stem cells

For the sake of the child: The economisation of reproduction in the Zika public health emergency

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