ZIFs derived polyhedron with cobalt oxide nanoparticles as novel nanozyme for the biomimetic catalytic oxidation of glucose and non-enzymatic sensor

Co‐based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences

“…In a recent study, Guangquan Mo and colleagues synthesized a more efficient nanozyme by injecting Co 3 O 4 NPs into nitrogen‐doped hollow carbon nanopolyhedra (NHCN‐Co 3 O 4 ). [ 115 ] The porous hollow N‐doped rhombic dodecahedral structure of NHCN‐Co 3 O 4 and the embedded Co 3 O 4 NPs enabled the nanozyme to directly oxidize glucose with an onset potential as low as 0.3 V, and a stable current signal could be detected within 3 s. The detection limit was as low as 0.2 µ m , and the stability, reproducibility, and interference immunity of the sensor allowed for reliable glucose detection. These breakthroughs demonstrate the promise of Co‐based nanozymes in electrochemical glucose sensing and provide new possibilities for glucose monitoring and disease prevention.…”

Recent Progress in MOF-Based Electrochemical Sensors for Non-Enzymatic Glucose Detection

“…The tests on human serum were not compared with clinical reports. As above, Ouyang et al [ 117 ] also prepared a non-enzymatic glucose sensor using ZIF-67. The difference was that Ouyang et al used a two-step redox pyrolysis to dope N into Co 3 O 4 hollow nanoparticles.…”

“… ( a ) N 2 adsorption-desorption isotherm of NHCN-Co 3 O 4 , and XPS spectrum of NHCN-Co 3 O 4 [ 117 ]. ( b ) Selectivity test at 0.45 V (a, b, c, d, e, f, g, h, and i: 3.0 μM UA, AA, DA, 0.30 mM leucine, glutamic acid, 0.30 mM alanine, pyruvic acid, lactic acid, and KCl); stability testing [ 117 ]; ( c ) SEM images of NiPO [ 114 ]. …”

Direct electrochemistry of doxorubicin and its ultra-sensitive detection using a novel porous thorny carbon dodecahedron

“…31 Significantly, the peak at 532.9 eV is the fingerprint peak of the O vacancy, also known as O defects that existed in the metal oxide. 30 The O vacancies have been revealed as the active sites for many crucial electrocatalytic reactions, e.g., CO 2 reduction, O 2 reduction, and O 2 evolution. 35,36 31 The ratio of Co 2+ to Co 3+ was calculated to be 0.73, suggesting that less CoO existed in Co 3 O 4 nanospheres.…”

“…23,24 With the ZIFs-67 template, highly active electrocatalysts containing multiple active centers, such as N species, O vacancies, and Co 3+/2+ species were acquired by the high-temperature carbonization treatment, which presented superb electrocatalysis towards oxygen reduction reaction, 24 water splitting reaction, 25 and CO 2 reduction reaction. 26 Besides, by the carbonization of the ZIFs-67 template, ZIF-derived electrocatalysts with efficient mass transfer, fast electron transfer, and solid polyhedral structure have been applied to the specific catalysis of small analytes, including hydrogen peroxide, 27,28 glucose, 29,30 L-cysteine, 31 uric acid, 32 and nitrophenol, 33 leading to an excellent sensing platform with significantly-boosted detection performance. However, as for the drug analytes of macromolecules, barely any reports can be referred to in terms of electrocatalysis, detection performance, and real applications.…”