2007
DOI: 10.1007/s10544-007-9139-2
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Zeta potential: a surface electrical characteristic to probe the interaction of nanoparticles with normal and cancer human breast epithelial cells

Abstract: We demonstrate the use of surface Zeta potential measurements as a new tool to investigate the interactions of iron oxide nanoparticles and cowpea mosaic virus (CPMV) nanoparticles with human normal breast epithelial cells (MCF10A) and cancer breast epithelial cells (MCF7) respectively. A substantial understanding in the interaction of nanoparticles with normal and cancer cells in vitro will enable the capabilities of improving diagnostic and treatment methods in cancer research, such as imaging and targeted d… Show more

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Cited by 365 publications
(226 citation statements)
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References 28 publications
(34 reference statements)
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“…Stability of the metal complexes is crucially important for many applications and can be determined using zeta potential measurements [18]. Zeta potential is the net surface charge of the nanoparticles when they are inside a solution.…”
Section: Particle Size and Zeta Potentialmentioning
confidence: 99%
“…Stability of the metal complexes is crucially important for many applications and can be determined using zeta potential measurements [18]. Zeta potential is the net surface charge of the nanoparticles when they are inside a solution.…”
Section: Particle Size and Zeta Potentialmentioning
confidence: 99%
“…were conducting experiments that focused on the biosensor field, to develop different methods for the determination of various ions and analytes [20]. Among the different biosensors, biosensors based on nanomaterials are very useful for biomolecular recombination pathogenic diagnosis and environmental monitoring applications [20][21][22][23].…”
Section: Introductionmentioning
confidence: 99%
“…Among the different biosensors, biosensors based on nanomaterials are very useful for biomolecular recombination pathogenic diagnosis and environmental monitoring applications [20][21][22][23]. The nano-size of a surface and the fast interaction with the target analytes on the surface make biosensors based on a nanomaterial able to detect analytes even in small volumes.…”
Section: Introductionmentioning
confidence: 99%
“…At pH 7.4, ALN results in positive zeta potentials, while RIS results in negative ones as a function of concentration, most likely due to the differing nitrogen charges/species among the two bisphosphonates. (1) Cells may sense and react to this potential, (46)(47)(48)(49)(50)(51)(52)(53) thus it is plausible that the different affinities and zeta-potentials influence osteoblastic function differently, quantitatively and/or qualitatively.…”
Section: Discussionmentioning
confidence: 99%