Zeolitic-imidazolate framework (ZIF-8)-based immobilized multi-enzymes integrated with a colorimetric sensor for cholesterol assay

Abstract

Co-immobilization strategies are available to improve the catalytic activity, stability and reusability of enzymes. It is applied in reactions involving multi-step catalysis to optimize the performance frequently in recent years....

A novel design of superparamagnetic iron oxide-based metal–organic framework for SSI-assisted drug delivery system

“…21 As another porous material, ZIF-8 possesses wider application in DDSs since it has a larger specific surface area, adjustable pore size, higher heat stability, and better biodegradability compared to UiO-66. 31 It is now well established from a variety of studies that ZIF-8 is recognized as a common nanocarrier for loading medicine, protein, and DNA. 32–34 Curcumol (CUR), a food source compound isolated from herbal medicine plant, has been reported to exert anticancer effects in multiple tumour cell lines without any side effects.…”

Zeolitic Imidazolate Framework-8 Composite-Based Enzyme-Linked Aptamer Assay for the Sensitive Detection of Deoxynivalenol

“…To address this problem, an enormous amount of effort has been devoted to developing HRP-based composites for the improvement of HRP’s stability [ 12 ]. A wide variety of nanomaterials including metal–organic frameworks (MOFs) [ 13 ], multi-walled carbon nanotubes [ 14 ] and graphene oxide [ 15 ], with ease of preparation, excellent thermal stability as well as great versatility, have been used for enzyme immobilization. Particularly, a great deal of attention has been drawn to MOFs for their remarkable properties of ultra-high porosity, good biocompatibility, multi-metal sites and large surface area [ 16 , 17 , 18 , 19 ].…”