Zeolites Applications in Veterinary Medicine

Abstract

Zeolites have a wide range of use, from construction industries, aquaculture industries, agriculture, space research to human and veterinary medicine. This broad application of natural and synthetic zeolites is given by their main properties: adsorption, molecular sieving and cation exchange capacity. In this chapter the main use of zeolites in veterinary medicine is reviewed. The beneficial effects of zeolites in animal nutrition, on mycotoxins, as an adjuvant in anticancer treatment and in increasing passive immunity of newborn ruminants are reported. Furthermore, multiple advantageous immune effects of zeolites such as their antioxidant capacity or their non-specific superantigen-like immunoglobulin action are also reviewed. Finally, their main positive effect on passive immunity in newborn calves is discussed. Literature data reviewed confirms their beneficial role in newborn calves during colostral period.

Integrated Metabolomics and Proteomics Dynamics of Serum Samples Reveals Dietary Zeolite Clinoptilolite Supplementation Restores Energy Balance in High Yielding Dairy Cows

“…Several reports over the years have investigated the different benefits and safety of using CPL to improve the health and energy status of animals [19][20][21]. However, limited information is available on the change of global metabolomics and proteomic profiles in serum that could provide a better understanding of the biological pathways and associated altered metabolic and proteomic status due to CPL supplementation during NEB.…”

Clinoptilolite Microparticles as Carriers of Catechin-Rich Acacia catechu Extracts: Microencapsulation and In Vitro Release Study

“…Later on, a significant decline of such type of investigations was observed, probably due to the emerging interest in various biopolymer formulations as efficient drug excipients. However, nowadays, a revival of studies on the potential of the natural zeolitic tuff as a drug-carrier candidate is of utmost importance due to its essential and indisputable physicochemical properties—non-toxicity, thermal stability, expanded surface area, exceptional ion-exchange and adsorption capacity towards ions and organic molecules [ 1 ], biocatalytic potential and a number of biological activities [ 2 ].…”

Effects of Thermal Treatment on Natural Clinoptilolite-Rich Zeolite Behavior in Simulated Biological Fluids

“…There are a high number of studies that report the properties of natural zeolites from different deposits after alkaline (NaOH, KOH), acidic (HCl, H 3 PO 4 , H 3 BO 3 ), and thermal treatments [8,[14][15][16][17]. Additionally, the beneficial properties of purified zeolites in human and veterinary medicine were recently reported [4,18].…”

“…Natural zeolites (mainly clinoptilolite) were successfully used for organism detoxification, as antidiarrheal and antiacid agents, and as adjuvant in anticancer therapy. The addition of zeolites to feeds enhanced the immunity of new-born ruminants and the gastrointestinal absorption of toxic compounds, reduces the deposition of radioactive compounds and the oxidative stress, boosting the growth performance of animals [17,19]. Due to their ability to encapsulate different ions and molecules, zeolites may be used in drug formulation as carriers for oral drugs and gene delivery.…”