2022
DOI: 10.21203/rs.3.rs-2378742/v1
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Zeolite-Y loaded chitosan nanoparticles nanocomposite as endodontic intra-canal medicament: synthesis, antimicrobial and cytotoxic activity: An in vitro study

Abstract: Objectives To synthesize a bioactive nanocomposite intra-canal medicament using chitosan nanoparticles (Ch-Np), loaded into Zeolite-Y as a carrier, and evaluate its antimicrobial activity in the presence and absence of tissue inhibitors. Also, to evaluate its cytotoxic activity against fibroblast cells. Materials and methods A concentration of 3% (w/v) electrosprayed Ch-Np was mixed with Zeolite-Y in a concentration of 53.3 (w/v) and characterized using Scanning Electron Microscopy (SEM), and Energy Dispersi… Show more

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