“…Despite the frequent presence of peripheral neurofibromas in NF 1, an intramedullary location is rare, with reports of only four solitary spinal intramedullary schwannomas in patients with NF 1,4,10,13,14) and only one case of multiple intramedul lary schwannomas in a patient without associated neurofibromatosis. 5) The occurrence of nerve sheath tumors in an intramedullary location raises im portant questions regarding the histogenesis.…”