2011
DOI: 10.1007/s12268-011-0065-8
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Zellspezifische Aptamere in Diagnostik und Therapie

Abstract: Mittels Zell-SELEX lassen sich Aptamere selektieren, die intakte Zellen spezifisch erkennen. Anwendungen liegen in der Identifizierung von Zellpopulationen sowie in der Therapie, da zellspezifische Aptamere regulatorische Effekte auf Zielzellen ausüben oder Wirkstoffe vermitteln können.Cell-SELEX allows the selection of aptamers that specifically recognize live target cells. Applications include isolation and identification of cell populations or their constituents. Furthermore, some of these aptamers show reg… Show more

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