Zeitgemäßes Management von nicht kognitiven Symptomen bei Demenz

Rainer, Michael; Mucke, Hermann Am; Masching, Andreas; Haushofer, Manfred; Karger, Martin; Kasper, S.; Kurz, Alexander

doi:10.1055/s-2003-814885

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…These may have somatic causes, including hyperthyroidism, disturbances of glucose metabolism, digitalis overdose, anticholinergic side effects, and psychoactive drug overdose (12). Visual and auditory impairment also promote delusions, as was already described by Kraepelin in 1915 ("Verfolgungswahn der Schwerhö-rigen," the persecution mania of the deaf).…”

Section: Somatic Causes Of Behavioral Disorders In Dementiamentioning

confidence: 94%

The Diagnosis and Treatment of Behavioral Disorders in Dementia

Kratz¹

2017

Deutsches Ärzteblatt International

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Section: Somatic Causes Of Behavioral Disorders In Dementiamentioning

confidence: 94%

The Diagnosis and Treatment of Behavioral Disorders in Dementia

Kratz¹

2017

Deutsches Ärzteblatt International

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“…Demenzkranken dar [20], denen im häuslichen Milieu häufig schwerer zu begegnen ist. Der fünfte Altenbericht der Bundesregierung kommt zu dem Ergebnis, dass bei pflegenden Angehörigen das Wissen um die Bedürfnisse der an Demenz leidenden Personen oft nicht ausreichend ist [3].…”

Section: Mangelernährung Und Dehydrierung Zentrale Probleme Der Pflegunclassified

“…Durch die professionelle Versorgung kann im Seniorenheim besonders auf somatische Probleme meist besser eingegangen werden [11]. So stellen Mangelernährung und Dehydrierung zentrale Probleme der Pflege von Demenzkranken dar [20], denen im häuslichen Milieu häufig schwerer zu begegnen ist. Der fünfte Altenbericht der Bundesregierung kommt zu dem Ergebnis, dass bei pflegenden Angehörigen das Wissen um die Bedürfnisse der an Demenz leidenden Personen oft nicht ausreichend ist [3].…”

Section: Introductionunclassified

Leben Demenzkranke zu Hause länger als im Heim?

et al. 2010

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Efficacy and Tolerability of Risperidone, Yokukansan, and Fluvoxamine for the Treatment of Behavioral and Psychological Symptoms of Dementia

Teranishi¹,

Kurita²,

Nishino³

et al. 2013

Journal of Clinical Psychopharmacology

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The descriptive term behavioral and psychological symptoms of dementia (BPSD) is used to cover a range of noncognitive disturbances including anxiety, depression, irritability, aggression, agitation, eating disorders, and inappropriate social or sexual behaviors. Behavioral and psychological symptoms of dementia are seen in about 90% of patients with dementia. We aimed to compare the efficacy and tolerability of risperidone, yokukansan, and fluvoxamine used for BPSD in elderly patients with dementia. Ninety inpatients with dementia according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria were investigated in Sato Hospital, Koutokukai. We conducted an 8-week, rater-blinded, randomized trial, administering flexibly dosed risperidone, yokukansan, or fluvoxamine. Primary outcome measures were Neuropsychiatric Inventory in Nursing Home Version total score and its items. Secondary outcome measures were cognitive function measured by Mini-Mental State Examination and daily life function measured by Functional Independence Measure (FIM). Neurological adverse effects were measured by the Drug-Induced Extra-Pyramidal Symptoms Scale. At the end of the study, we analyzed 76 patients (92.7%). Mean Neuropsychiatric Inventory in Nursing Home Version total score decreased in all 3 drug groups, with no significant between-group differences. Mini-Mental State Examination and Functional Independence Measure scores did not change significantly. Drug-Induced Extra-Pyramidal Symptoms Scale scores did not change in the yokukansan and fluvoxamine groups, but increased significantly in the risperidone group. Risperidone, yokukansan, and fluvoxamine were equally effective in the treatment of BPSD in elderly patients. However, yokukansan or fluvoxamine for BPSD showed a more favorable profile in tolerability compared with risperidone. This trial is registered at UMIN Clinical Trials Registry (identifier: UMIN000006146).

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Zeitgemäßes Management von nicht kognitiven Symptomen bei Demenz

Abstract: Psychiatrists at memory clinics in German-speaking Europe have therapeutic attitudes and practices that are consistent with the current state of the art.

Cited by 5 publications

References 11 publications

The Diagnosis and Treatment of Behavioral Disorders in Dementia

The Diagnosis and Treatment of Behavioral Disorders in Dementia

Leben Demenzkranke zu Hause länger als im Heim?

Efficacy and Tolerability of Risperidone, Yokukansan, and Fluvoxamine for the Treatment of Behavioral and Psychological Symptoms of Dementia

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