ZC3H13 Enhances the Malignancy of Cervical Cancer by Regulating m6A Modification of CKAP2
Yuan Zhang,
Xiaoqing Chen,
Huiqun Chen
et al.
Abstract:Sustained expression of zinc finger CCCH-type containing 13 (ZC3H13) in tumors is essential for cancer cell malignancy; however, our understanding of its clinical effects and mechanisms in cervical cancer (CC) is limited. In this study, we aimed to reveal the effect on CC progression of ZC3H13-mediated N6-methyladenosine (m6A) modification to stabilize cytoskeleton-associated protein 2 (CKAP2) expression. CC tissues and paired adjacent normal tissues were collected from 50 patients. qRT-PCR was used to clarify… Show more
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