Abstract:Nitric oxide (NO) plays an important role in metabolism. Consequently, every tissue of our body is affected by changes in concentrations of nitric oxide and its metabolites. Here we analyze phenotypic effects of NO and its metabolites in macrophages, NK-cells and lymphocytes that perform protection of the host organism against malignant tumors and intracellular pathogens. Immune system imbalance may result from misregulation of NO synthesis. Nitric oxide also plays an important role in endothelial dysfunction … Show more
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