Abstract:ABSTRACT:We have carried out solid supported ,solvent free condition, microwave assisted rapid synthesis of 1-(2,5-substituted diphenyl)-1, 3, 4-oxadiazol -3(2H) -yl) ethanone (3a-3k) by cyclization of N'-(substituted phenyl methylidene) substituted benzohydrazide (2a-2k) in the presence of acetic anhydride and silica gel ( solid support) for 3-4 minutes by microwave irradiation giving excellent yield in short reaction time are notable advantages of this method. The structure elucidations of all the synthesize… Show more
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