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Abstract

Brain and kidneys from 15 control and 70 experimental puppies with hemodynamic model of coarctation of the aorta were examined. The number of regulatory muscle formations was increased in the brain and decreased in the kidneys during modeling of aorta coarctation associated with hyper- and hypotension in the corresponding basins. The location of these structures in cerebral and renal distribution and resistance vessels is analyzed.

Polyploidy of smooth myocytes in coronary arteries

“…Coarctation of the aorta was created surgically [7] in experiments on eighteen 3-4-month-old puppies. After 1 year the defect was repaired in 8 of them and the animals were observed for 12 months.…”

Structural remodeling of the renal vascular bed during experimental pulmonary stenosis and after its correction

“…Pulmonary stenosis was followed by remodeling of the renal vascular bed and adaptive and pathological reconstruction of veins, arteries, and glomeruli. Correction of the defect was followed by regression of pathological changes.Study of morphological reconstruction of the vascular system in vital organs (e.g., kidneys) during circulatory disorders typical of congenital heart diseases is an urgent medical problem [4,6,9,12]. Little is known about reversibility of this reconstruction.…”

“…Study of morphological reconstruction of the vascular system in vital organs (e.g., kidneys) during circulatory disorders typical of congenital heart diseases is an urgent medical problem [4,6,9,12]. Little is known about reversibility of this reconstruction.…”