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Abstract

Introduction: Hypertension is common disorder and leading cause of morbidity and mortality worldwide. Proteinuria has recently been identified as a cardiovascular risk marker in hypertensive patients. In this view left ventricular hypertrophy was studied with reference to hypertension and 24 hours proteinuria. Aims: To study left ventricular hypertrophy, 24 hours proteinuria and their co-relation in hypertensive subjects. Material and methods: The study was cross sectional type including 100 hypertensive subjects attending medicine department. The hypertensives with renal disease, ischaemic heart disease excluded from the study. Esbach's method to estimate 24 hour urine protein was used. Left ventricular hypertrophy(LVH) was determined by 2-D echo using Devereux formula. Statistical analysis was done.Result: Mean Proteinuria for the duration of hypertension ≤5 years was 0.27±0.13 and for the duration of >5 years it was 0.44±0.14(z-value=6.04,p-value =0.000).Mean LVH for the duration of hypertension ≤5 yr was 118.55±31.81 and for the duration of >5 years it was 231.74±53.71(z-value=3.87,p-value =0.000).Significant positive co-relation was found between proteinuria and LVH(r=0.350, p-value=0.000 and Mean ±2SD of correlation of 0.012 to 0.392) which means that as LVH increases proteinuria also increases significantly. Conclusion: Hypertensive subjects develop proteinuria. As duration of hypertension increases, left ventricular hypertrophy and proteinuria also increases.