Youth Knowledge and Perspectives on Expedited Partner Therapy

Jamison, Cornelius D.; Waselewski, Marika; Gogineni, Vinaya; Bell, Jasmine A.; Hadler, Nicole; Chaudhry, Kiren Aziz; Chang, Tammy; Mmeje, Okeoma

doi:10.1016/j.jadohealth.2021.06.021

Cited by 4 publications

(4 citation statements)

References 12 publications

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“…As most adolescents use mobile phones in their day-to-day lives, professional apps that provide an anonymous, free, and voluntary platform for information were considered [ 30 , 31 ]. Additionally, getting treatment for partners may be effective in reducing STI incidence in youth [ 32 ]. Second, effective STI prevention interventions include screening, contact tracing of sexual partners, and promoting effective barrier contraception [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Increasing incidence rates of sexually transmitted infections from 2010 to 2019: an analysis of temporal trends by geographical regions and age groups from the 2019 Global Burden of Disease Study

Yan

Jing

et al. 2022

BMC Infect Dis

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Background World Health Organization announced its goal of ending sexually transmitted infection (STI) epidemics by 2030. To provide a reference for tailored prevention strategies, we analyzed trends and differences in STIs by geographical regions and age groups from 1990 to 2019. Methods Annual number of new infections and age-standardized incidence rates (ASRs) of syphilis, chlamydia, gonorrhea, trichomoniasis, and genital herpes were recorded from the 2019 Global Burden of Disease study. We quantified the temporal trends of STIs by calculating changes in new infections and estimated annual percentage changes (EAPCs) of ASR. Results The ASRs of syphilis, chlamydia, trichomoniasis, and genital herpes increased by 1.70% (95% confidence interval [CI], 1.62–1.78%), 0.29% (95% CI 0.04–0.54%), 0.27% (95% CI 0.03–0.52%), and 0.40% (95% CI 0.36–0.44%) per year from 2010 to 2019 worldwide, respectively, while that of gonorrhea did not. The American regions had the greatest increase in ASR for syphilis (tropical Latin America: EAPC, 5.72; 95% CI 5.11–6.33), chlamydia (high-income North America: EAPC, 1.23; 95% CI 0.73–1.73), and gonorrhea (high-income North America: EAPC, 0.77; 95% CI 0.12–1.41). Additionally, southern sub-Saharan Africa and East Asia had the greatest increase in ASR for trichomoniasis (EAPC, 0.88; 95% CI 0.57–1.20) and genital herpes (EAPC, 1.44; 95% CI 0.83–2.06), respectively. In the most recent years, the population with the greatest incidence of syphilis tended to be younger globally (25–29 years in 2010 vs. 20–24 years in 2019) but older in North Africa and Middle East (20–24 year vs. 25–29 years); with chlamydia tended to be older in southern sub-Saharan Africa (25–29 years vs. 30–34 years) but younger in Australasia (40–44 years vs. 25–29 years); with genital herpes tended to be older in high-income North America (20–24 years vs. 25–29 years) and South Asia (25–29 years vs. 30–34 years). Conclusions Syphilis, chlamydia, trichomoniasis, and genital herpes showed a trend of increasing ASR from 2010 to 2019. The differences in trends by geographical regions and age groups point to the need for more targeted prevention strategies in key regions and populations.

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Section: Discussionmentioning

confidence: 99%

Increasing incidence rates of sexually transmitted infections from 2010 to 2019: an analysis of temporal trends by geographical regions and age groups from the 2019 Global Burden of Disease Study

Yan

Jing

et al. 2022

BMC Infect Dis

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“…It is established through tens of studies of different designs that gonorrhea as well as chlamydia, being curable infections, carry a high risk of reinfection because of re-exposure to the same sexual partner or to other high-risk partners. (11,(13)(14)(15) As such, it can be assumed that a current gonorrhea infection is strongly indicative of previous gonorrhea infection; (11,16,17) indeed studies have shown that the strongest predictor of current gonorrhea infection is a history of gonorrhea infection. (10,18) For example, in the UK, a history of gonorrhea infection was found to be the strongest predictor of current gonorrhea infection even after controlling for other demographic and behavioral factors (adjusted OR 4.36, 95% CI 1.78 to 10.71).…”

Section: Introductionmentioning

confidence: 99%

Association of Chlamydia trachomatis and Neisseria gonorrhoeae with female infertility: a systematic review and meta-analysis

Majnooni

Jamedar²,

Azimian

et al. 2022

Univ Med

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BackgroundChlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are commonly diagnosed sexually transmitted infections that have been associated with serious reproductive health outcomes for women. The association of CT and NG infection with female fertility is not completely established yet. This review aimed to determine the association of CT and NG with female infertility. MethodsThis systematic review and meta-analysis was conducted according to the PRISMA statement. We searched a range of electronic databases, including PubMed, Web of Science, Embase, and Scopus, from Sept 25, 2017 until February 1, 2021. From the 851 studies screened, 552 that failed to meet our eligibility criteria were excluded. Subsequently, we removed 290 studies for not having a possible correlation of CT and NG infections with female infertility. Nine studies comprising 1827 infertile patients met our inclusion criteria. Two investigators independently extracted a range of data. All analyses were performed using STATA (version 13.1, Stata Corp, College Station, TX, USA). ResultsCT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them. However, due to the limited number of reported data, we were not able to compare NG infection prevalence in fertile and non-fertile patients. Overall prevalences of CT and NG infections among infertile patients were 12 % and 3%, respectively, while CT infection prevalence among the fertile group was 7%. Conclusion The prevalences of CT and NG infections were high in infertile women. Screening and treatment of C. trachomatis and gonococcal infections during infertility treatment might increase the pregnancy rate.

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“…5 Although evidence on EPT effectiveness in adolescents is limited, it seems to be acceptable to them. 6,7 Provision of EPT has the potential to increase the willingness of sexual partners to accept treatment and reduces barriers to accessing treatment. Numerous medical organizations including the CDC and the Society for Adolescent Health and Medicine have endorsed EPT.…”

mentioning

confidence: 99%

“…Expedited partner therapy is currently legal in 46 states, including Colorado 5 . Although evidence on EPT effectiveness in adolescents is limited, it seems to be acceptable to them 6,7 . Provision of EPT has the potential to increase the willingness of sexual partners to accept treatment and reduces barriers to accessing treatment.…”

mentioning

confidence: 99%

Reducing Barriers for Expedited Partner Treatment in Adolescents and Young Adults: A Quality Improvement Initiative

Richards,

Bogart,

Sheeder

2024

Sexual Trans Dis

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Background Adolescents and young adults (AYA) face significant barriers to screening, testing and treatment for sexually transmitted infections (STIs). Expedited partner therapy (EPT) streamlines partner treatment for STIs but use among adolescents is low. We aimed to increase EPT offering and provision at two adolescent medicine clinics (AMC) and the emergency department (ED) in an urban children’s hospital. We addressed barriers at provider, pharmacy, and patient levels. We compared EPT offering and provision for chlamydia (CT) and trichomonas (TV) infection at baseline, and across two intervention cycles. Methods Baseline data was collected from 7/2019-3/2020 and our intervention time frame spanned from April 2020-October 2021. Laboratory codes identified patients with CT or TV infections. Cycle one allowed providers to order EPT within a patient’s chart. The second cycle targeted education and standardization for STI/EPT notification and counseling. During this cycle, notification of ED patients was centralized to the AMC nurses. Results A total of 747 CT and TV cases were identified. In the AMC, EPT offering increased from 77.3% to 87.7% (p = 0.01). EPT provision increased from 32.3% to 69.9% (p < 0.001). EPT offering for ED patients increased by 82.3%. Retesting rates remained consistent, with a significant drop in reinfection rates (p = 0.003) within patients seen in the AMC. Conclusions This QI initiative successfully increased EPT offering and provision among the cases identified. Future cycles may include longer-term follow up to confirm partner treatment and testing per guidelines.

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Youth Knowledge and Perspectives on Expedited Partner Therapy

Cited by 4 publications

References 12 publications

Increasing incidence rates of sexually transmitted infections from 2010 to 2019: an analysis of temporal trends by geographical regions and age groups from the 2019 Global Burden of Disease Study

Increasing incidence rates of sexually transmitted infections from 2010 to 2019: an analysis of temporal trends by geographical regions and age groups from the 2019 Global Burden of Disease Study

Association of Chlamydia trachomatis and Neisseria gonorrhoeae with female infertility: a systematic review and meta-analysis

Reducing Barriers for Expedited Partner Treatment in Adolescents and Young Adults: A Quality Improvement Initiative

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