Younger age at initiation of subcutaneous treprostinil is associated with better response in pediatric Group 1 pulmonary arterial hypertension
Justin J. Kochanski,
Jeffrey A. Feinstein,
Michelle Ogawa
et al.
Abstract:Children with severe Group 1 pulmonary arterial hypertension (PAH) have an unpredictable response to subcutaneous treprostinil (TRE) therapy, which may be influenced by age, disease severity, or other unknown variables at time of initiation. In this retrospective single‐center cohort study, we hypothesized that younger age at TRE initiation, early hemodynamic response (a decrease in pulmonary vascular resistance by ≥30% at follow‐up catheterization), and less severe baseline hemodynamics (Rp:Rs < 1.1) would… Show more
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