Right Ventricle 2018
DOI: 10.1183/13993003.congress-2018.oa1637
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Young males with pulmonary arterial hypertension have a high afterload and low right ventricular ejection fraction at presentation

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“…Women, despite being more prone to PAH development, exhibit improved survival and superior RV function than their male counterparts, suggesting oestrogens are the mediators of improved RV function [ 55 ]. As sex hormone levels change with ageing in both sexes, G roeneveldt et al [ 56 ] explored, for the first time, the effect of age on PAH disease severity and RV adaptation in both sexes (n=298). RV function at baseline was not related to age in women; however, young men presented an increased afterload, and increased RV volume and mass when compared to men >50 years old.…”
Section: Pulmonary Hypertensionmentioning
confidence: 99%
“…Women, despite being more prone to PAH development, exhibit improved survival and superior RV function than their male counterparts, suggesting oestrogens are the mediators of improved RV function [ 55 ]. As sex hormone levels change with ageing in both sexes, G roeneveldt et al [ 56 ] explored, for the first time, the effect of age on PAH disease severity and RV adaptation in both sexes (n=298). RV function at baseline was not related to age in women; however, young men presented an increased afterload, and increased RV volume and mass when compared to men >50 years old.…”
Section: Pulmonary Hypertensionmentioning
confidence: 99%