Yoga and breathing technique training in patients with heart failure and preserved ejection fraction: study protocol for a randomized clinical trial

Abstract

BackgroundCurrent therapies for heart failure (HF) are followed by strategies to improve quality of life and exercise tolerance, besides reducing morbidity and mortality. Some HF patients present changes in the musculoskeletal system and inspiratory muscle weakness, which may be restored by inspiratory muscle training, thus increasing respiratory muscle strength and endurance, maximal oxygen uptake (VO2), functional capacity, respiratory responses to exercise, and quality of life. Yoga therapies have been shown to improve quality of life, inflammatory markers, and peak VO2 mostly in HF patients with a reduced ejection fraction. However, the effect of different yoga breathing techniques in patients showing HF with a preserved ejection fraction (HFpEF) remain to be assessed.Methods/designA PROBE (prospective randomized open blinded end-point) parallel-group trial will be conducted at two specialized HF clinics. Adult patients previously diagnosed with HFpEF will be included. After signing informed consent and performing a pre-test intervention, patients will be randomized into three groups and provided with either (1) active yoga breathing techniques; (2) passive yoga breathing techniques (pranayama); or and (3) control (standard pharmacological treatment). Follow-up will last 8 weeks (16 sessions). The post-intervention tests will be performed at the end of the intervention period for analysis of outcomes. Interventions will occur continuously according to patients’ enrollment. The main outcome is respiratory muscular resistance. A total of 33 enrolled patients are expected. The present protocol followed the SPIRIT guidelines and fulfilled the SPIRIT checklist.DiscussionThis trial is probably the first to assess the effects of a non-pharmacological intervention, namely yoga and specific breathing techniques, to improve cardiorespiratory function, autonomic system, and quality of life in patients with HFpEF.Trial registrationREBEC Identifier: RBR-64mbnx (August 19, 2012).Clinical Trials Register: NCT03028168. Registered on 16 January 2017).Electronic supplementary materialThe online version of this article (10.1186/s13063-018-2802-5) contains supplementary material, which is available to authorized users.

Role of mind–Body intervention on lipid profile: A cross-sectional study

“…[ 21 ] Regular exercise, yoga asanas, pranayama, and meditation have been shown to prevent and correct these abnormalities[ 22 23 ] Studies point to the beneficial effect of yoga in maintaining physiological balance of lipid profile parameters[ 6 24 3 ] and prevention of the related cardiac complications. [ 26 ] Other studies[ 27 ] also point to the beneficial effects of physical exercises in ameliorating dyslipidemia by upregulating HDL levels and downregulating LDL and TGL;[ 28 ] it has been reported that HDL seems to play a key role in maintaining triglyceride levels. [ 29 ] Further, Kumari et al ., 2013,[ 30 ] looking at the mechanism points out that Yoga practices may improve the lipid profile in by elevating hepatic lipase activity which may facilitate better triglyceride metabolism in the adipose tissue.…”

Inspiratory Muscle Training in Patients With Heart Failure With Preserved Ejection Fraction: A Meta-Analysis

“…It showed no change in the pooled results after excluded individual studies. An RCT on the role of yoga and breathing exercise in HFpEF is currently ongoing so we couldn’t analyze its data but once it will be complete, it will certainly be helpful to explore more on the topic of breathing [ 6 ].…”

“…In our study, we have shifted our gaze to evaluate inspiratory muscle training for improving quality of life and cardiorespiratory fitness in patients with stable HFpEF. We have used peak oxygen consumption (Peak VO 2 ) and six-min walk distance (6MWD) as a marker of cardiorespiratory fitness and quality of life in HFpEF patients [4,[6][7][8][9].…”

Alternative Medicine for Fight against Covid-19/Coronavirus and “Alternative” Treatments

“…Ayurveda boosts comprehensive wellbeing, which include eating routine, rest, mental unwinding, way of life conduct, and Yoga Pranayama (Breathing techniques) is known to enhance lung capacity. (Lopes et al, 2018) Yoga and meditation are simple and affective for various other illnesses also. (Tillu et al, 2020a).…”