Yoga als Möglichkeit zur Reduktion von Fatigue bei Multiple Sklerose

Garis, Guadalupe; Hildebrandt, Herbert; Hanken, Katrin

doi:10.14624/nr2101006

Cited by 3 publications

(1 citation statement)

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“…Abnormalities in vagal power in MS have been detected at slower respiratory rates during paced breathing exercises, as reflected by lower HF power in the variantundefined MS group than HC, at 8, 12 and 15 breaths per minute (b.p.m), but not at 18 b.p.m [56]. Further, a recent review demonstrated that yoga practices, which heavily rely on deep breathing exercises, may be particularly helpful in alleviating MS-related fatigue [68], arguing for a temporary increase in PANS activity. Judging from this evidence, increasing HRV through deep breathing exercises could presumably produce body autonomic activity characteristic of relaxation in MS patients, helping to restore parasympathetic balance.…”

Section: Hrv Adaptation In Rest and During Orthostatic Challengementioning

confidence: 99%

Heart rate variability and fatigue in MS: two parallel pathways representing disseminated inflammatory processes?

et al. 2022

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Background Fatigue is a disabling symptom of multiple sclerosis. Its biological causes are still poorly understood. Several years ago, we proposed that fatigue might be the subjective representation of inflammatory processes. An important step for a straight-forward evaluation of our model would be to show that the level of fatigue is associated with vagal activation. The heart rate is under partial control of the vagus nerve. Using power spectrum analysis allows to separate, at least partly, sympathetic and parasympathetic impact on heart rate variability. Methods This narrative review summarizes the evidence for heart rate variability changes in MS patients, their relationship with fatigue and disease course. To do this, we conducted a literature search, including 45 articles relevant to the topic treated in this review. Results We illustrate that (1) inflammation leads to a change in cardiac behavior during acute and chronic phases, both in animals and in humans; (2) MS patients show changes of heart rate variability (HRV) that resemble those during acute and chronic inflammation due to multiple causes; (3) existing evidence favors a set of specific predictions about fatigue and parallel HRV changes; and (4) that MS-related brainstem lesions or neurological impairments do not completely explain HRV changes, leaving enough place for an explanatory relation between HRV and fatigue. Discussion We discuss the results of this review in relation to our model of fatigue and propose several observational and experimental studies that could be conducted to gain a better insight into whether fatigue and HRV can be interpreted as a common pathway, both reflecting activated autoimmune processes in MS patients.

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Section: Hrv Adaptation In Rest and During Orthostatic Challengementioning

confidence: 99%

Heart rate variability and fatigue in MS: two parallel pathways representing disseminated inflammatory processes?

et al. 2022

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Comparing two relaxation procedures to ease fatigue in multiple sclerosis: a single-blind randomized controlled trial

Garis,

Dettmers,

Hildebrandt

et al. 2023

Neurol Sci

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Background Various relaxation procedures have been proposed to reduce fatigue in multiple sclerosis (MS). However, it is unknown, which type of relaxation has the largest effect on fatigue reduction and on autonomic nervous system (ANS) activity. Objective We aimed to compare two biofeedback-supported relaxation exercises: a deep breathing (DB) exercise and progressive muscle relaxation (PMR), which may ameliorate MS fatigue and alter ANS activity. Methods We performed a single-blind randomized clinical trial, introducing MS patients (n = 34) to the DB or PMR exercise. We first tested cardiovagal integrity, reflected by changes in heart rate variability (HRV) in response to DB. Participants then performed a fatigue-inducing vigilance task, followed by the DB or PMR. State fatigue was recorded consecutively at baseline, after the vigilance task, and after the relaxation exercise, along with HRV reflecting ANS activity. Results Only patients assigned to the PMR group experienced a significant drop in fatigue, whereas both relaxation exercises changed ANS activity. MS patients showed the expected autonomic response during the cardiovagal reflex test. The vigilance task elevated short-term feelings of fatigue and significantly reduced HRV parameters of parasympathetic activity. Trait fatigue was negatively correlated with HRV during the second half of the vigilance task. Conclusion PMR alleviates short-term feelings of fatigue in persons with MS. The vigilance task in combination with HRV measurements may be helpful for evaluating relaxation procedures as a treatment of fatigue. Hereby, future studies should ensure longer and more frequent relaxation exercises and focus on patients with weak to moderate fatigue. Trial registration Trial Registry: DRKS00024358.

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Ambulante Physiotherapie bei Multipler Sklerose mit sekundär chronisch progredientem Verlauf

Becker¹,

Saner²

2022

Fallbuch Physiotherapie: Neurologie

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Yoga als Möglichkeit zur Reduktion von Fatigue bei Multiple Sklerose

Cited by 3 publications

References 0 publications

Heart rate variability and fatigue in MS: two parallel pathways representing disseminated inflammatory processes?

Heart rate variability and fatigue in MS: two parallel pathways representing disseminated inflammatory processes?

Comparing two relaxation procedures to ease fatigue in multiple sclerosis: a single-blind randomized controlled trial

Ambulante Physiotherapie bei Multipler Sklerose mit sekundär chronisch progredientem Verlauf

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