Field trials including two plant cane crops and one 1 st ratoon were conducted in El-Mattana Agric. Res. Station, (latitude of 25.17° N and longitude of 32.33° E), Esna, Luxor Governorate, Egypt, during the two successive seasons of 2013/2014 and 2014/2015 to find out the performance of three sugar cane varieties (G.T. 54-9, G. 2003-47 and G.2003-49), which were planted using two planting densities (1.5 drills "37800 buds/fed" and 2 drills "50400 buds/fed") and fertilized with three nitrogen levels (180, 210 and 240 kg N/fed "fed = 0.42 ha-1"). A randomized complete block design (RCBD) using split-plot arrangement with three replications was used. The varieties were allocated in the main plots, mean while planting densities and nitrogen levels were randomly distributed in the sub-plot. The important results could be summarized as follow:Variety G.T.54-9 over passed the two promising varieties in length, diameter and fresh weight/plant of stalks. The two promising varieties (G.2003-47 and G.2003-49) over passed the commercial variety (G.T.54-9) in brix, purity and sugar recovery percentages and number of millable in the three crops. Variety G.2003-47 gave the highest sugar yield in the two crops and ratoon.Planting density 37800 buds/fed attained a significant increase in stalk diameter compared with planting by 50400 buds/fed, meanwhile, the same planting density i.e. 37800 buds/fed produced the higher stalk fresh weight in the two plant cane crops and 1 st ratoon. Planting density 50400 buds/fed attained the highest taller stalks, brix, purity and sugar recovery percentages, number of millable cane/fed and cane and sugar yields/fed, meanwhile, the same density reduced glucose % in the different crops.Increasing nitrogen levels up to 240 kg N/fed led to significantly increased in stalk length, stalk diameter, stalk fresh weight/plant, number of millable cane/fed, cane yield/fed and sugar yield/fed for the three cane crops. Increased nitrogen levels from 180 to 210 and 240 kg N/fed caused significant increase sugar yield/fed in the three cane crops, this increment amounted by 15.67 and 23.24 % in the 1 st planted cane, 13.83 and 18.81% in the 1 st ratoon and 6.45 and 8.10 % in the 2 nd planted cane, respectively.The highest number of millable cane/fed was recorded when sugar cane planted with 50400 buds/fed and fertilized by 240 kg N/fed.Variety G.T.54-9 attained the highest stalk fresh weight values with the different nitrogen levels over the two promising varieties. The best interaction was between variety G.2003-47 and 210 kg N/fed to produce the highest purity % in the three crops. The interaction between the varieties and nitrogen levels attained a significant influence on sugar recovery % in the 1 st ratoon and the 2 nd planted cane.