“Yes, I’m interested in taking PrEP!”: PrEP interest among women respondents to the European community-based survey “Flash! PrEP in Europe”

Delabre, Rosemary M.; Bernier, Adeline; Sánchez, Flor; Vilotitch, Antoine; Chanos, Sophocles; Cosmaro, Maria Luisa; Langanke, Harriet; Mey, Coline; James, Cary; Duken, Sascha Béla; Schlegel, Vincent; Stranz, Richard; Jonas, Kai J.; Spire, Bruno; Castro, Daniela Rojas

doi:10.1371/journal.pone.0246037

Cited by 8 publications

(11 citation statements)

References 50 publications

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“…Lower levels of knowledge in and use of PrEP by women are in line with existing literature (29), despite recent European data showing the interest of women who are at high risk of acquiring HIV in accessing PrEP (40), underlining the relevance of a targeted information strategy to reach women at high risk.…”

Section: Discussionsupporting

confidence: 76%

Knowledge and Use of PEP and PrEP Among Key Populations Tested in Community Centers in Portugal

Simões

Meireles

Rocha³

et al. 2021

Front. Public Health

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Background: Pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) have been increasingly available in Europe. Due to the high burden of HIV in key populations, these could benefit from their use. In 2016, in Portugal, an open, non-interval, prospective cohort study was established in a network of 26 community-based voluntary HIV/STI counseling and testing centers. Data collected included questions on PEP and PrEP knowledge and use. We aimed to estimate the proportion of PEP and PrEP knowledge and its use among key populations, visiting the centers between 2016 and 2019.Method and results: Individuals who self-identify as being among at least one key population for HIV, men who have sex with men (MSM), people who inject drugs (PWID), sex workers (SW), migrants, and male-to-female transgender individuals (MTF), responded to questions on PEP and PrEP knowledge and use while waiting for their test results between 2016 and 2019 (n = 12,893 for PEP; n = 10,973 for PrEP). Reported knowledge was low in all key populations for both tools: 15.7% of respondents reported knowing about PEP and 10.9% about PrEP over the course of 4 years. PEP was used by 1.8% and PrEP by 0.4% of the respondents, MSM being 88.9% of PrEP users, and 52.8% of PEP users. Multivariate logistic regression showed multiple factors associated with knowing the tools, including age, education, country of birth, gender, year of test, having a reactive HIV test in the same visit, reporting an STI or condomless sex in the last 12 months, and identifying with being MSM or SW.Conclusions: Knowledge and use of PEP and PrEP remain low among key populations in Portugal. The need remains to increase knowledge and use among those at risk for HIV infection.

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Section: Discussionsupporting

confidence: 76%

Knowledge and Use of PEP and PrEP Among Key Populations Tested in Community Centers in Portugal

Simões

Meireles

Rocha³

et al. 2021

Front. Public Health

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“…Finally, 44 original studies represented in 45 peer‐reviewed articles were included. See Figure 1 [10–42] [43–53].…”

Section: Resultsmentioning

confidence: 99%

“…Six studies, including 1009 women, examined awareness of and willingness to use PrEP [14, 25, 32, 43, 48, 50]. Generally, PrEP awareness was low, but once information on PrEP was provided, most participants across these studies viewed PrEP as a potential prevention option they would use.…”

Section: Resultsmentioning

confidence: 99%

PrEP for women in Europe: a systematic literature review

et al. 2023

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Background: Prevention of HIV transmission is fundamental to ending the HIV epidemic. Pre-exposure prophylaxis (PrEP) with oral tenofoviremtricitabine (TDF-FTC) is an established HIV-prevention method; however, most PrEP services in Europe have been targeted at men who have sex with men (MSM). A survey in 2021 by Women Against Viruses in Europe (WAVE) showed considerable variation in PrEP access and guidance for women throughout Europe. WAVE therefore commissioned this systematic review to provide insight into PrEP provision and barriers to uptake for women in Europe.Methods: PubMed, Embase, and Scopus were searched for studies (January 2013-May 2021) that reported on actual (e.g., efficacy and safety) or hypothetical (e.g., awareness, barriers, PrEP impact models) use of oral PrEP involving women (including cis, transgender, pregnant, migrant, and breastfeeding women). Search terms included HIV, pre-exposure prophylaxis (specifically TDF-FTC), and women. Studies performed outside of the World Health Organization European region were excluded. Results:The search identified 4716 unique citations, and 45 peer-reviewed articles (44 studies) were included. The majority of these studies (34/44 [77%])

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“…Through the survey, the respondents provided information regarding sociodemographic characteristics, sexual behaviors, currently used prevention strategies, self-reported HIV status, access to sexual health care, drug consumption behavior, history of PEP use and knowledge, interest, intention, and current or past use of PrEP. Detailed information about the study survey and its promotion has been previously published (Delabre et al, 2021 ).…”

Section: Methodsmentioning

confidence: 99%

PrEP in the Context of Other HIV Risk Reduction Strategies Among Men Who Have Sex with Men: Results from the Flash! PrEP in Europe Survey

Ciaccio

Delabre²,

Vilotitch

et al. 2022

Arch Sex Behav

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Combination HIV prevention covers a range of biomedical, behavioral, and socio-structural interventions. Despite the growing availability of pre-exposure prophylaxis (PrEP), it is not always accessible in European Centre for Disease Prevention and Control reporting countries and may not meet the needs of all at-risk populations. Based on the Flash! PrEP in Europe data, multiple correspondence analysis and hierarchical clustering were used to identify patterns in HIV prevention strategies among 9980 men who have sex with men (MSM). PrEP interest was evaluated among four identified clusters: (A) “high condom use, sometimes Treatment as Prevention (TasP)”; (B) “mix of methods, infrequent condom use”; (C) “high condom use, tendency to choose partners based on serological status” and (D) “moderate use of condoms mixed with other prevention strategies”. Clusters B and D had higher PrEP interest. These results suggest that MSM use a range of behavioral and biomedical risk reduction strategies that are often combined. On-demand PrEP may meet the needs of MSM who infrequently use condoms and other prevention methods.

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“Yes, I’m interested in taking PrEP!”: PrEP interest among women respondents to the European community-based survey “Flash! PrEP in Europe”

Cited by 8 publications

References 50 publications

Knowledge and Use of PEP and PrEP Among Key Populations Tested in Community Centers in Portugal

Knowledge and Use of PEP and PrEP Among Key Populations Tested in Community Centers in Portugal

PrEP for women in Europe: a systematic literature review

PrEP in the Context of Other HIV Risk Reduction Strategies Among Men Who Have Sex with Men: Results from the Flash! PrEP in Europe Survey

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