Yellow-Pigmented Pathogenic Mycobacteria From Cervical Lymphadenitis

Abstract

Among 14 strains of yellow-pigmented acid- and alcohol-fast rods isolated from human pathological materials, 10 strains from tuberculoid lesions of cervical or facial lymphadenitis in children merit particular interest. They were compared with some of the mycobacteria, including Mycobacterium tuberculosis, and with Nocardia. On the basis of morphology, staining properties, cultural characteristics, pathogenicity, and allergic reactions in laboratory animals, they have been placed in the genus Mycobacterium. However, the degree and quality of their differences from other named species of the genus as observed under the present experimental conditions, and the fact of their isolation in pure culture from closed lesions, has led to the proposal that they be given the name Mycobacterium scrofulaceum n. sp.

Classification of Scotochromogenic Mycobacteria

“…However, since the original strain of Galli-Valerio has at present been lost, it is difficult to identify the present pathogenic scotochromogens as Galli-Valerio's M. aquae. The name M. scrofulaceurn may be appropriate because the significance of pathogenic scotochromogens has been re-recognized by this organism [6][7][8].…”

Epidemiology and Clinical Significance of Nontuberculous Mycobacteria in Patients Negative for Human Immunodeficiency Virus in Switzerland

“…First reports of NTM associated with this localization date back to the 1950s. In 1956 Prissick and Masson [94] found a scotochromogenic NTM species in 25 children with cervicallymphadenitis and proposed the name M. scrofulaceum. As reviewed by Lincoln and Gilbert [95], NTM was responsible for superficiallymphadenitis in children in an increasing number of cases.…”

Numerical Classification of Atypical Mycobacteria

“…1 and Table 2), they may be named M. terrae, M. avium, M. in- tracellulare and M. aquae (scrofulaceum). The name M. intracellulare was proposed by Runyon [15] for the pathogenic non.-photochromogens (Battey bacilli), and the names M. aquae and M. scrofulaceum were proposed by BOnicke [4] and by Prissick and Masson [12,13], respectively, for a group of the scotochromogens. According to our studies, the pathogenic scotochromogens isolated in Japan were all identified as M. scrofulaceum, and M. scrofulaceum was identical to M. aquae [30].…”

“…Since these four groups of organisms could be roughly differentiated by numerical classification ( Fig. 1 and Table 2), they may be named M. terrae, M. avium, M. in- [12,13], respectively, for a group of the scotochromogens. According to our studies, the pathogenic scotochromogens isolated in Japan were all identified as M. scrofulaceum, and M. scrofulaceum was identical to M. aquae [30].…”