“Yellow nail syndrome” associated with chronic recurrent pericardial and pleural effusions

Morandi, Uliano; Golinelli, M; Brandi, Luis; Ruggiero, C; Stefani, Alessandro; Lodi, Renzo

doi:10.1016/s1010-7940(05)80048-x

Cited by 7 publications

(5 citation statements)

References 5 publications

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“…Pericardial effusion, which is rarely described in this syndrome, was related to hypoalbuminemia or lymphedema. 7 The presence of minimal pericardial effusion in our patient supports this diagnosis.…”

Section: Discussionsupporting

confidence: 79%

Yellow Nail Syndrome in an Infant Presenting with Lymphedema of the Eyelids and Pleural Effusion

Yalçın

Gönç

Çetinkaya

et al. 2004

Clin Pediatr (Phila)

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Section: Discussionsupporting

confidence: 79%

Yellow Nail Syndrome in an Infant Presenting with Lymphedema of the Eyelids and Pleural Effusion

Yalçın

Gönç

Çetinkaya

et al. 2004

Clin Pediatr (Phila)

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“…One hundred and twelve studies involving 150 patients were selected for review, spanning a period of nearly 50 years. Figure presents a flow chart for the complete breakdown in the identification of appropriate studies . They all corresponded to the description of isolated case reports (between 1 and 4 per item) and a retrospective series of 19 patients…”

Section: Resultsmentioning

confidence: 99%

“…53 Three patients presented with a pericardial effusion. 61,67,82 In one case, both pericardiocentesis and pericardial drainage were not effective, so clinicians had to resort to a pericardiotomy. 61 In the other two, pericardial drainage 72 and performing a pericardial window 82 led to favourable progress.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of patients with yellow nail syndrome and pleural effusion

et al. 2014

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Yellow nail syndrome (YNS) can be associated with a pleural effusion (PE) but the characteristics of these patients are not well defined. We performed a systematic review across four electronic databases for studies reporting clinical findings, PE characteristics, and most effective treatment of YNS. Case descriptions and retrospective studies were included, unrestricted by year of publication. We reviewed 112 studies (150 patients), spanning a period of nearly 50 years. The male/female ratio was 1.2/1. The median age was 60 years (range: 0-88). Seventy-eight percent were between 41-80 years old. All cases had lymphoedema and 85.6% had yellow nails. PEs were bilateral in 68.3%. The appearance of the fluid was serous in 75.3%, milky in 22.3% and purulent in 3.5%. The PE was an exudate in 94.7% with lymphocytic predominance in 96% with a low count of nucleated cells. In 61 of 66 (92.4%) of patients, pleural fluid protein values were >3 g/dL, and typically higher than pleural fluid LDH. Pleurodesis and decortication/pleurectomy were effective in 81.8% and 88.9% of cases, respectively, in the treatment of symptomatic PEs. The development of YNS and PE occurs between the fifth to eighth decade of life and is associated with lymphoedema. The PE is usually bilateral and behaves as a lymphocyte-predominant exudate. The most effective treatments appear to be pleurodesis and decortication/pleurectomy.

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“…5 Based on our literature review, there are only 10 previous reports of YNS with pericardial effusion reported in the literature. [6][7][8][9][10][11][12][13][14][15] All reported cases to date have also had associated pleural effusion(s).…”

Section: Discussionmentioning

confidence: 99%

Yellow Nail Syndrome Presenting With a Pericardial Effusion: A Case Report and Review of the Literature

Soong

Haber

2017

J Cutan Med Surg

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Yellow nail syndrome (YNS) is a constellation of clinical findings including at least 2 of the 3 features of thickened yellow nails, respiratory tract involvement, and lymphedema. We report the case of a middle-aged man presenting with dystrophic, thickened yellow nails; an idiopathic pericardial effusion in the absence of pleural effusion(s); and unilateral apical bronchiectasis found on computed tomography of the chest. This represents a unique presentation of YNS as the first report of a patient with YNS and a pericardial effusion in the absence of pleural effusions and lymphedema and is the 11th case report of YNS with pericardial effusion.

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“Yellow nail syndrome” associated with chronic recurrent pericardial and pleural effusions

Cited by 7 publications

References 5 publications

Yellow Nail Syndrome in an Infant Presenting with Lymphedema of the Eyelids and Pleural Effusion

Yellow Nail Syndrome in an Infant Presenting with Lymphedema of the Eyelids and Pleural Effusion

Characteristics of patients with yellow nail syndrome and pleural effusion

Yellow Nail Syndrome Presenting With a Pericardial Effusion: A Case Report and Review of the Literature

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