Yellow fever revaccination during infliximab therapy

EULAR recommendations for vaccination in paediatric patients with rheumatic diseases

“…In addition, evidence supports the safety of VZV, MMR and YFV booster vaccines in patients on methotrexate less than 15 mg/m 2 per week or low-dose glucocorticosteroids 17 63–65…”

“…The measles, mumps, rubella (MMR) booster and yellow fever virus (YFV) booster were safe in patients on methotrexate less than 15 mg/m 2 per week (n=118), various DMARD (sulphasalazine, leflunomide, cyclosporine, cyclophosphamide), anti-TNFα (n=28) and rituximab (n=3) 35 63–65. Similarly, primary varicella zoster virus (VZV) vaccination did not induce severe adverse events or disease flares in 25 PaedRD patients on glucocorticosteroids, methotrexate, and/or various DMARD 17.…”

Yellow Fever Vaccination of a Primary Vaccinee during Adalimumab Therapy

“…The authors suggest that the absence of adverse events and the development of a humoral immune response in the majority of their patients could be explained by the presence of a persistent immune response after prime vaccination. 9 There are, however, no published reports about persons receiving their first dose of YFV while on treatment with TNF antagonists. Our patient represents the first reported reference.…”

Vaccination of Immunocompromised Travelers: Need for Specific Recommendations!

“…For patients receiving low doses of immunosuppressive drugs and/or biological immunomodulators for chronic inflammatory diseases, there are only few published data concerning safety and efficacy of live vaccine. 13,14 Until additional information becomes available, YF vaccination should be avoided, unless the benefit of vaccination outweighs the increased risk of adverse reaction. In patients taking systemic corticosteroids, the amount of systemically absorbed corticosteroids and duration of administration needed to suppress the immune system are not well defined.…”