“…In another study, Seynnaeve et al [18] showed the relevance of yeasts, especially S. cerevisiae, as a model to unravel mechanisms contributing to Synphilin-1-dependent pathology in the context of neurodegenerative diseases, such as Parkinson's disease and Lewy body dementia. They focused on understanding the influence of sugar metabolism disturbances promoting the glycation of proteins on the aggregation of Synphilin-1, which is a partner of α-Synuclein, a primary constituent of Lewy bodies.…”