Yeast as a biological platform for vitamin D production: A promising alternative to help reduce vitamin D deficiency in humans

Kessi-Pérez, Eduardo I.; González, Adens; Palacios, José Luis; Martı́nez, Claudio

doi:10.1002/yea.3708

Cited by 7 publications

(5 citation statements)

References 123 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, the level of vitamin D was positively associated with the consumption of sweet and baked goods, probably from the yeast used in baking (Kessi-Pérez et al, 2022) and from cocoa or chocolate that are among the common flavouring ingredients used in baked goods (Benedik, 2022). In addition, vitamin D was found to be positively associated with the consumption of beverages, most likely from fortified beverages.…”

Section: Discussionmentioning

confidence: 51%

Dietary pattern, nutrient intake, and oral symptoms in a sample of pregnant women in Malaysia

Ibrahim,

Saddki,

Hasan

2023

Mal J Nutr

View full text Add to dashboard Cite

Introduction: Nutritional requirements of pregnant women differ considerably from those of non-pregnant women. Nutritional status during pregnancy is critical to maintain health, including oral health, and to promote growth and development of the baby. This study assessed dietary pattern, nutrient intake, and oral symptoms among pregnant women. Methods: Seventy-one women with singleton pregnancy attending a public healthcare centre in Malaysia participated in this cross-sectional study. Dietary pattern and nutrient intake of the women were assessed using food frequency questionnaire and 3-day 24-hour diet recall, respectively. Information on sociodemographic and obstetric profiles, and oral symptoms were obtained from self-administered questionnaire. Results: White rice, chicken, green leafy vegetables, granulated sugar, and salt were foods most consumed. Intakes of iron, folate, vitamin C, vitamin D, calcium, iodine, zinc, and fluoride for most respondents were below Recommended Nutrient Intake (RNI). Cavitated tooth (46.5%), bleeding gums (35.2%), pain upon eating and drinking (23.9%), and bad breath (23.9%) were common oral symptoms reported. Significant association was found between complaint of brown, yellow, and white spots on tooth surface with vitamin A intake, and between complaint of bleeding gums with zinc intake. Conclusion: Intake of most nutrients by most respondents in this study was below the RNI. Oral symptoms were common and a few were associated with nutrient intakes.

show abstract

Section: Discussionmentioning

confidence: 51%

Dietary pattern, nutrient intake, and oral symptoms in a sample of pregnant women in Malaysia

Ibrahim,

Saddki,

Hasan

2023

Mal J Nutr

View full text Add to dashboard Cite

show abstract

“…Herein, we deployed this platform to evaluate the impact of three perturbation events: hydration (water amendment), nutri cation (media amendment), and contamination, via introduction of the industrial microbe, Saccharomyces cerevisiae (yeast). Yeast was selected because it is an industrially relevant microbe that is employed by multiple elds, including the production of biofuels [9][10][11][12]. It is important to note that the practical application of microbial technologies at scale may necessitate genetic modi cation of S. cerevisiae, despite the fact that the potential environmental impact of such modi cations, or even of a large scale contamination event with wild-type yeast, remain poorly understood.…”

Section: Introductionmentioning

confidence: 99%

Risk Assessment of Industrial Microbes Using a Terrestrial Mesocosm Platform

Arnolds

Higgins

Crandall

et al. 2023

Preprint

View full text Add to dashboard Cite

Industrial microbes and bio-derived products have emerged as an integral component of the bioeconomy, with an array of agricultural, bioenergy, and biomedical applications. However, the rapid development of microbial biotechnology raises concerns related to environmental escape of laboratory microbes, detection and tracking thereof, and resultant impact upon native ecosystems. Indeed, though wild-type and genetically modified microbes are actively deployed in industrial bioprocesses, an understanding of microbial interactivity and impact upon the environment is severely lacking. In particular, the persistence and sustained ecosystem impact of industrial microbes following laboratory release or unintentional laboratory escape remains largely unexplored. Herein, we investigate the applicability of soil-sorghum mesocosms for the ecological risk assessment of the industrial microbe, Saccharomyces cerevisiae. We developed and applied a suite of diagnostic and bioinformatic analyses, including digital droplet PCR, microscopy, and phylogenomic analyses to assess the impacts of a terrestrial ecosystem perturbation event over a 30-day time course. The platform enables reproducible, high sensitivity tracking of S. cerevisiae in a complex soil microbiome and analysis of the impact upon abiotic soil characteristics and soil microbiome population dynamics and diversity. The resultant data indicate that even though S. cerevisiae is relatively short-lived in the mesocosm, a single perturbation event can have sustained impact upon soil composition and underlying microbial populations, underscoring the necessity for more comprehensive risk assessment and development of mitigation and biocontainment strategies in industrial bioprocesses.

show abstract

“…Herein, we deployed this platform to evaluate the impact of three perturbation events: hydration (water amendment), nutrification (media amendment), and contamination, via introduction of the industrial microbe, Saccharomyces cerevisiae (yeast) . Yeast was selected because it is an industrially relevant microbe that is employed by multiple fields, including the production of biofuels [ 9 – 12 ]. It is important to note that the practical application of microbial technologies at scale may necessitate genetic modification of S. cerevisiae , despite the fact that the potential environmental impact of such modifications, or even of a large-scale contamination event with wild-type yeast, remains poorly understood [ 13 – 15 ].…”

Section: Introductionmentioning

confidence: 99%

Risk Assessment of Industrial Microbes Using a Terrestrial Mesocosm Platform

Arnolds,

Higgins,

Crandall

et al. 2023

Microb Ecol

View full text Add to dashboard Cite

Industrial microbes and bio-derived products have emerged as an integral component of the bioeconomy, with an array of agricultural, bioenergy, and biomedical applications. However, the rapid development of microbial biotechnology raises concerns related to environmental escape of laboratory microbes, detection and tracking thereof, and resultant impact upon native ecosystems. Indeed, though wild-type and genetically modified microbes are actively deployed in industrial bioprocesses, an understanding of microbial interactivity and impact upon the environment is severely lacking. In particular, the persistence and sustained ecosystem impact of industrial microbes following laboratory release or unintentional laboratory escape remains largely unexplored. Herein, we investigate the applicability of soil-sorghum mesocosms for the ecological risk assessment of the industrial microbe, Saccharomyces cerevisiae. We developed and applied a suite of diagnostic and bioinformatic analyses, including digital droplet PCR, microscopy, and phylogenomic analyses to assess the impacts of a terrestrial ecosystem perturbation event over a 30-day time course. The platform enables reproducible, high-sensitivity tracking of S. cerevisiae in a complex soil microbiome and analysis of the impact upon abiotic soil characteristics and soil microbiome population dynamics and diversity. The resultant data indicate that even though S. cerevisiae is relatively short-lived in the soil, a single perturbation event can have sustained impact upon mesocosm soil composition and underlying microbial populations in our system, underscoring the necessity for more comprehensive risk assessment and development of mitigation and biocontainment strategies in industrial bioprocesses.

show abstract

Yeast as a biological platform for vitamin D production: A promising alternative to help reduce vitamin D deficiency in humans

Cited by 7 publications

References 123 publications

Dietary pattern, nutrient intake, and oral symptoms in a sample of pregnant women in Malaysia

Dietary pattern, nutrient intake, and oral symptoms in a sample of pregnant women in Malaysia

Risk Assessment of Industrial Microbes Using a Terrestrial Mesocosm Platform

Risk Assessment of Industrial Microbes Using a Terrestrial Mesocosm Platform

Contact Info

Product

Resources

About