Year in Review 2019: High-Flow Nasal Cannula Oxygen Therapy for Adult Subjects

Li, Jie; Jing, Guoqiang; Scott, J Brady

doi:10.4187/respcare.07663

Cited by 40 publications

(35 citation statements)

References 70 publications

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“…Oxygen delivery via HFNC has become widely used in patients with acute hypoxemic respiratory failure due to its benefits of meeting or exceeding patient inspiratory flow demand, reducing oxygen dilution, and washing out pharyngeal dead space [ 55 ]. HFNC has been shown to reduce the need for endotracheal intubation when compared to conventional oxygen delivery devices [ 56 ].…”

Section: Literature Findings and Suggestionsmentioning

confidence: 99%

“…Pre-oxygenation prior to intubation plays a crucial role in avoiding complications during intubation. Multiple randomized controlled trials have shown that the utilization of HFNC for pre-oxygenation can help reduce the incidence of hypoxemia during intubation [ 55 , 80 ]. The cost-effectiveness and the high risk of transmission from high gas flows should be taken into consideration before using it for pre-oxygenation prior to intubation.…”

Section: Literature Findings and Suggestionsmentioning

confidence: 99%

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Practical strategies to reduce nosocomial transmission to healthcare professionals providing respiratory care to patients with COVID-19

et al. 2020

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Coronavirus disease (COVID-19) is an emerging viral infection that is rapidly spreading across the globe. SARS-CoV-2 belongs to the same coronavirus class that caused respiratory illnesses such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). During the SARS and MERS outbreaks, many frontline healthcare workers were infected when performing high-risk aerosol-generating medical procedures as well as when providing basic patient care. Similarly, COVID-19 disease has been reported to infect healthcare workers at a rate of ~ 3% of cases treated in the USA. In this review, we conducted an extensive literature search to develop practical strategies that can be implemented when providing respiratory treatments to COVID-19 patients, with the aim to help prevent nosocomial transmission to the frontline workers.

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Section: Literature Findings and Suggestionsmentioning

confidence: 99%

Section: Literature Findings and Suggestionsmentioning

confidence: 99%

Practical strategies to reduce nosocomial transmission to healthcare professionals providing respiratory care to patients with COVID-19

et al. 2020

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“…5 6 In hypoxaemic respiratory failure, HFNC use is associated with lower mortality, lower rates on endotracheal intubation and improved oxygenation. [7][8][9] It has been extensively used early in the COVID-19 outbreak in China. 10 Prone positioning (PP) of mechanically ventilated patients is an effective first-line Strengths and limitations of this study ► This pragmatic design will deal with the recruitment difficulties that could occur in the individual trials given the uncertainties of the international dynamics of the COVID-19 pandemic.…”

Section: Introductionmentioning

confidence: 99%

Awake prone positioning of hypoxaemic patients with COVID-19: protocol for a randomised controlled open-label superiority meta-trial

Tavernier

McNicholas

Pavlov³

et al. 2020

BMJ Open

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IntroductionProne positioning (PP) is an effective first-line intervention to treat patients with moderate to severe acute respiratory distress syndrome (ARDS) receiving invasive mechanical ventilation, as it improves gas exchanges and reduces mortality. The use of PP in awake spontaneous breathing patients with ARDS secondary to COVID-19 was reported to improve oxygenation in few retrospective trials with small sample size. High-level evidence of awake PP for hypoxaemic patients with COVID-19 patients is still lacking.Methods and analysisThe protocol of this meta-trial is a prospective collaborative individual participant data meta-analysis of randomised controlled open label superiority trials. This design is particularly adapted to a rapid scientific response in the pandemic setting. It will take place in multiple sites, among others in USA, Canada, Ireland, France and Spain. Patients will be followed up for 28 days. Patients will be randomised to receive whether awake PP and nasal high flow therapy or standard medical treatment and nasal high flow therapy. Primary outcome is defined as the occurrence rate of tracheal intubation or death up to day 28. An interim analysis plan has been set up on aggregated data from the participating research groups.Ethics and disseminationEthics approvals were obtained in all participating countries. Results of the meta-trial will be submitted for publication in a peer-reviewed journal. Each randomised controlled trial was registered individually, as follows: NCT04325906, NCT04347941, NCT04358939, NCT04395144 and NCT04391140.

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“…High‐flow nasal cannula (HFNC) oxygen therapy has increased in popularity in recent years due to its superiority over conventional oxygen therapy in reducing treatment failure, particularly among small children 1 . The utilization of HFNC has also been expanded from critical care units to general care wards, emergency departments, and procedure rooms 2 . There are several known physiologic benefits of HFNC oxygen therapy: meeting and/or exceeding patient inspiratory flow, providing a constant fraction of inspired oxygen (F I O 2 ) and a small amount of positive airway pressure, and washing out the anatomic dead space 1‐3 .…”

mentioning

confidence: 99%

Defining the optimal role of high‐flow nasal cannula in pediatric procedural sedation

Scott

Lee

2020

Pediatric Pulmonology

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Year in Review 2019: High-Flow Nasal Cannula Oxygen Therapy for Adult Subjects

Cited by 40 publications

References 70 publications

Practical strategies to reduce nosocomial transmission to healthcare professionals providing respiratory care to patients with COVID-19

Practical strategies to reduce nosocomial transmission to healthcare professionals providing respiratory care to patients with COVID-19

Awake prone positioning of hypoxaemic patients with COVID-19: protocol for a randomised controlled open-label superiority meta-trial

Defining the optimal role of high‐flow nasal cannula in pediatric procedural sedation

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