Untitled

doi:10.13040/ijpsr.0975-8232.8(8).3187-93

Cited by 3 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The colonies formed in the Petri dishes are then calculated using the colony counter (Scan®300Interlab, France) machine. A concentration is considered MBC when said concentration can reduce 98-99% from the initial number of bacteria [18,19].…”

Section: Antibacterial Testmentioning

confidence: 99%

Effectiveness of Batak Leeks Extract Against S. Mutans and E. Faecalis as Antibacterial and Antibiofilm Agent

OCTIARA,

ADINDA,

SEMBIRING

2024

Int J App Pharm

View full text Add to dashboard Cite

Objective: S. mutans biofilms have become the main cause of dental caries. Meanwhile, E. faecalis biofilms cause endodontic infection. Batak leeks are native North Sumatra herb that contains antibacterial properties. This study aims to determine Batak leeks extract's antibacterial and antibiofilm effectiveness towards S. mutans and E. faecalis. Methods: This study was a laboratory experimental research with a posttest-only control group design. The sample size was 27, consisting of 3 samples each with concentrations of 0.78%; 1.56%; 3.25%; 6.25%; 12.5%; 25% and 50% Batak leek extract and 3 negative control samples and 3 positive. The Kirby-Bauer disc diffusion method was used to determine MIC, the streaking method to determine MBC and the Static Microtiter Plate Assays method for antibiofilm determination. Data analysis used Oneway ANOVA and Kruskall Wallis tests followed by post-hoc LSD and Mann-Whitney tests. Results: The results showed that Batak leeks extract contained MIC values at 0,78% concentration levels with an average inhibitory zone of 6,80±0,10 mm in S. mutans and E. faecalis. MBC values were undetected because there were no group capable of reducing bacteria at 98-98% and the highest antibiofilm reduction was found in 50% concentration extract with values of 85.58% for S. mutans and 90.29% for E. faecalis. Conclusion: It concluded that 0.78% concentration of Batak leeks extract has an antibacterial effect, but at 50% concentration was the most influential in inhibiting S. mutans and E. faecalis, and antibiofilm ability starts at the concentration level of 1.56%.

show abstract

Section: Antibacterial Testmentioning

confidence: 99%

Effectiveness of Batak Leeks Extract Against S. Mutans and E. Faecalis as Antibacterial and Antibiofilm Agent

OCTIARA,

ADINDA,

SEMBIRING

2024

Int J App Pharm

View full text Add to dashboard Cite

show abstract

“…Distinct zones were observed in the inhibition zone surrounding the wells following incubation. The inhibition area was measured in mL using a digital calliper [18,19]. The activity index was determined using the subsequent formula:…”

Section: Determination Of the Minimum Inhibitory Concentrationmentioning

confidence: 99%

Untitled

2023

J. Med. Chem. Sci.

View full text Add to dashboard Cite

Antibacterial Activity of Durian Peel Ethanol Extract (Durio zibethinus Murr.) against Streptococcus mutans and Enterococcus faecalis

Octiara,

Meliala,

Sikumbang

2023

Biomed. Pharmacol. J.

View full text Add to dashboard Cite

Dental caries and root canal infections are common dental and oral diseases due to the dominance of S.mutans and E.faecalis. Despite not having any economic value and becoming a waste, durian peel is claimed as an antibacterial. This study aims to analyze durian peel ethanol extract antibacterial activity against S.mutans and E.faecalis based on the inhibition zone diameter, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). This type of research is a laboratory experiment using Post-test Only Control Group Design. There were 7 concentrations of durian peel ethanol extract (50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, and 0.78%), both positive and negative control with three times repetitions. Moreover, the bacterial suspensions used were S.mutans ATCC 25175 and E.faecalis ATCC 29212. Data analysis used One Way Anova, while data that were not normally distributed used Kruskal-Wallis. Post Hoc analysis used LSD for normal data and Mann-Whitney for abnormal data. Durian peel ethanol extract shows the antibacterial activity of S.mutans with MIC at a concentration of 0.78%, while against E.faecalis is 12.5%. The higher the concentration, the larger the inhibition zone formed. The best-tested concentration of ethanol extract from durian peel is 6.25-50% to inhibit the growth of S. mutans and 50% for E.faecalis. Durian peel ethanol extract can prevent dental caries since it is antibacterial against S.mutans and E.faecalis.

show abstract

Untitled

Cited by 3 publications

References 25 publications

Effectiveness of Batak Leeks Extract Against S. Mutans and E. Faecalis as Antibacterial and Antibiofilm Agent

Effectiveness of Batak Leeks Extract Against S. Mutans and E. Faecalis as Antibacterial and Antibiofilm Agent

Untitled

Antibacterial Activity of Durian Peel Ethanol Extract (Durio zibethinus Murr.) against Streptococcus mutans and Enterococcus faecalis

Contact Info

Product

Resources

About