2020
DOI: 10.4314/tjpr.v19i3.21
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Yangjing capsule attenuates cyclophosphamide-induced deficiency of testicular microcirculation in mice

Abstract: Purpose: To explore the protective effects of Yangjing capsule (YC) on testicular microcirculation in a mouse model of deficiency of testicular microcirculation. Methods: Immunohistochemistry was applied to determine the effects of YC on microvascular density of mice. The protein level of CD34 and vascular endothelial growth factor A (VEGF A) was measured by western blot. The viability of Testicular cell line (TM4 cells) was examined by CCK-8 assay. Results: Histopathological changes demonstrated t… Show more

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Cited by 6 publications
(6 citation statements)
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References 22 publications
(33 reference statements)
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“…Central nervous system complications following surgery in older adults are characterized by confusion, anxiety, personality changes, and impaired memory [9,10]. Such changes in personality, social skills, and cognitive abilities and skills are referred to as POCD [11].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Central nervous system complications following surgery in older adults are characterized by confusion, anxiety, personality changes, and impaired memory [9,10]. Such changes in personality, social skills, and cognitive abilities and skills are referred to as POCD [11].…”
Section: Discussionmentioning
confidence: 99%
“…Immunoblot assays were performed similar to a previous study [9]. Brains were extracted, and proteins were lysed with RIPA buffer (Beyotime Biotechnology, Shanghai, China), isolated using a 10% SDS-PAGE, transferred onto PVDF membranes, and blocked with 5% fat-free milk in TBST buffer.…”
Section: Immunoblot Assaymentioning
confidence: 99%
“…Mediation of the balance of Th17 cells and Treg cells can improve sepsis-induced ALI. Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the nuclear hormone receptor family and one of the PPAR isotypes [5]. PPARγ activation plays anti-inflammatory and anti-apoptotic roles in several inflammatory diseases, including ALI.…”
Section: Introductionmentioning
confidence: 99%
“…Cerebral ischemia-reperfusion (I/R) usually refers to patients who have suffered from MI, where the use of reperfusion is equivalent to ischamic preconditioning because of multiple occlusions occurring within minutes after reperfusion. Thrombolysis, primary angioplasty, and cardiac surgery are effective treatments to restore blood flow to ischemic myocardium (Jin et al, 2020). As a disease with high mortality and morbidity, MI still lacks more effective treatments, and hence an in-depth study of its pathogenesis is urgently required (Singh et al, 2021).…”
Section: Introductionmentioning
confidence: 99%